endocannabinoids

Exercise exerts a wide range of beneficial effects for healthy physiology1. However, the mechanisms regulating an individual’s motivation to engage in physical activity remain incompletely understood. An important factor stimulating the engagement in both competitive and recreational exercise...

The work was done in mice. The method used to modulate dopamine levels - optogenetics - was new to me, and fascinating. The researchers think their work has relevance to depression and PTSD. Should low dopamine levels prove to be relevant in ME, some of the results from the study may also...