depression

Exploring predictors of post-COVID-19 condition among 810 851 individuals in Sweden BACKGROUND Long-term effects of COVID-19 can place burden on individuals, healthcare, and society. We aimed to evaluate the importance of a wide range of potential risk factors for being diagnosed with...

Schizophrenia, Bipolar, or Major Depressive Disorder and Postacute Sequelae of COVID-19 IMPORTANCE Given the increased vulnerability to COVID-19 among those with a serious mental illness (SMI), it remains unclear whether these individuals face a higher risk of developing postacute sequelae of...

Fatigue, cognitive complaints, dyspnea, anxiety, and depression as post-COVID syndrome: a cross-sectional study in Sfax, Southern Tunisia INTRODUCTION post-COVID refers to symptoms and health problems that continue or develop after the initial phase of a COVID-19 infection has resolved. It...

Genome-wide association study of adolescent-onset depression Abstract Adolescent depression is a heritable psychiatric condition with rising global prevalence and severe long-term outcomes, yet its biological underpinnings remain poorly understood. We conducted the first genome-wide...

Associations of selective serotonin reuptake inhibitors and long COVID risk in patients with depression: a retrospective cohort study PURPOSE To evaluate the potential of selective serotonin reuptake inhibitors (SSRIs) in reducing the risk of long COVID in patients with depression. METHODS...

Large responses to antidepressants or methodological artifacts? A secondary analysis of STAR∗D, a single-arm, open-label, nonindustry antidepressant trial https://www.sciencedirect.com/science/article/pii/S0895435625002768 Objectives To replicate Stone et al's (2022) finding that the...

https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2025.1623757/full Background: Mental symptoms such as fatigue, concentration difficulties, and sleep disorders are frequently reported in both Post-COVID Syndrome (PCS) and Post-COVID-19 Vaccination Syndrome (PCVS)...

Sex-stratified genome-wide association meta-analysis of major depressive disorder Jodi T. Thomas, Jackson G. Thorp, Floris Huider, Poppy Z. Grimes, Rujia Wang, Pierre Youssef, Jonathan R. I. Coleman, Enda M. Byrne, Mark Adams, BIONIC consortium, The GLAD Study, Sarah E. Medland, Ian B. Hickie...

Prospective associations between major depressive disorder, generalized anxiety disorder, fibromyalgia, and myalgic encephalomyelitis/chronic fatigue syndrome Nathaniel Stembridge Thomas, Michael C. Neale, Kenneth S. Kendler, Hanna M. van Loo, Nathan A. Gillespie Background Functional...

Effect of nonpharmacologic therapies on depressive symptoms in patients with chronic fatigue syndrome: a network meta-analysis Baiyi Jiang, Mengru Cao, Xue Xia, Long Wang Background Depression or depressive symptoms exacerbate the burden in patients with chronic fatigue syndrome (CFS). The...

Long COVID and its associations with burnout, anxiety, and depression among U. S. healthcare workers in the United States BACKGROUND Data on Long COVID and its associations with burnout, anxiety and depression among healthcare workers (HCW) in the United States (U. S.) is limited. METHODS...

Peripheral leptin receptor gene network modulates the impact of childhood adversity on mental health disorders Sobreira de Lima; Barth; Arcego; de Mendonça Filho; Patel; Wang; Elgbeili; Pokhvisneva; Parent; Levitan; Kobor; Dalmaz; Silveira Psychiatric disorders are highly prevalent and often...

Disentangling nature and nurture: Exploring the genetic background of depressive symptoms in the absence of recent stress exposure using a GWAS approach Berta Erdelyi-Hamza, Dora Torok, Sandor Krause, Nora Eszlari, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda Highlights • Heterogeneity of...

Chronic stress remodels brain homeostasis, in which persistent change leads to depressive disorders. As a key modulator of brain homeostasis, it remains elusive whether and how brain autophagy is engaged in stress dynamics. Here we discover that acute stress activates, whereas chronic stress...

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study Eleni Friligkou, Solveig Løkhammer, Brenda Cabrera-Mendoza, Jie Shen, Jun He, Giovanni Deiana, Mihaela Diana Zanoaga, Zeynep Asgel, Abigail Pilcher, Luciana Di Lascio...

Affective disorders and chronic inflammatory conditions: Analysis of 1.5 million participants in Our Future Health Arish Mudra Rakshasa-Loots, Duncan Swiffen, Christina Steyn, Katie F. M. Marwick, Daniel J. Smith [Line breaks added] Abstract Chronic inflammation is associated with psychiatric...

Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes Abstract Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic...

[Neither the paper nor even the title of the paper seems to be available yet based on a quick search] https://www.eurekalert.org/news-releases/1084605 News Release 20-May-2025 Study finds alarming rates of anxiety and depression in children with long COVID Kennedy Krieger Institute research...

Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions Christina Dardani, Jamie W. Robinson, Hannah J. Jones, Dheeraj Rai, Evie Stergiakouli, Jakob Grove, Renee Gardner, Andrew M. McIntosh, Alexandra Havdahl, Gibran...

An Alternative Approach to Future Diagnosis: Can Generalized Anxiety Disorder Be Distinguished From Major Depressive Disorder, Healthy People by Differentially Expressed lncRNAs in Peripheral Blood Lingming Kong, Liang Zhang [Line breaks added] Purpose Symptomatic diagnosis combined with...