https://www.medrxiv.org/content/10.1101/2025.04.08.25325108
Abstract
Post-COVID Syndrome (PCS), also known as Long COVID, is characterized by persistent and often debilitating neurological sequelae, including fatigue, cognitive dysfunction, motor deficits, and autonomic dysregulation (Dani et...
Potential Mechanisms Underlying COVID-19-Mediated Central and Peripheral Demyelination: Roles of the RAAS and ADAM-17
Oliveira, Kellysson Bruno; de Souza, Fernanda Maria Araujo; de Sá, Letícia Barros Maurício; Pacheco, Amanda Larissa Dias; Prado, Mariana Reis; de Sousa Rodrigues, Célio Fernando...
The role of Sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disorders
Paola Giussani; Alessandro Prinetti; Cristina Tringali
Multiple sclerosis (MS) represents the most common demyelinating disease affecting the central nervous system...
Here we report preliminary data demonstrating that some patients with myalgic encephalomyelitis/chronic fatiguesyndrome (ME/CFS) may have catalytic autoantibodies that cause the breakdown of myelin basic protein (MBP). We propose that these MBP-degradative antibodies are important to the...
Myelin lipid metabolism and its role in myelination and myelin maintenance
Barnes-Vélez JA, Aksoy Yasar FB, Hu J
Myelin is a specialized cell membrane indispensable for rapid nerve conduction. The high abundance of membrane lipids is one of myelin's salient features that contribute to its...
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