clinical trials

I thought this press release including "Up to 18 new Commercial Research Delivery Centres (CRDCs) will be established across the 4 nations to enhance and build upon the UK’s commercial clinical trials infrastructure and support patient recruitment into trials. " was of interest. See...

Abstract Long COVID is a debilitating, multisystemic illness following a SARS-CoV-2 infection whose duration may be indefinite. Over four years into the pandemic, little knowledge has been generated from clinical trials. We analyzed the information available on ClinicalTrials.gov, and found...

Abstract Most of the people who suffered from COVID-19 fully recovered, but approximately 10–20% of them developed a wide variety of symptoms after they recover from their initial illness. Long COVID can develop at any patient; however, several studies suggest that the development of Long Covid...

As the title indicates -- a thread for lay people like me who have no or only superficial knowledge of trial methodology and statistics to ask some basic questions and hopefully get answers from more knowledgeable forum members.

Dall'Era, M., Bruce, I. N., Gordon, C., Manzi, S., McCaffrey, J., & Lipsky, P. E. (2019). Current challenges in the development of new treatments for lupus. Annals of the rheumatic diseases, 78(6), 729–735. https://doi.org/10.1136/annrheumdis-2018-214530...

Full title: Statistical power in clinical trials of interventions for mood, anxiety, and psychotic disorders Authors: Ymkje Anna de Vries, Robert A Schoevers, Julian P T Higgins, Marcus R Munafò, Jojanneke A Bastiaansen Published: Psychological medicine, May 2022 Link...