chronic pain

Pathogen-specific exposure is associated with multisite chronic pain: A prospective cohort study Jialiu Fang, Zemene Demelash Kifle, Jing Tian, Silvana Bettiol, Flavia Cicuttini, Graeme Jones, Feng Pan [Line breaks added] Abstract Evidence suggests that pathogens may influence pain perception...

Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One‐Sample Mendelian Randomization Study Maryam Kazemi Naeini, Maxim B Freidin, Isabelle Granville Smith, Stephen Ward, Frances M K Williams Background Chronic back pain (CBP) is a major cause of...

Good in depth article—mentions fibromyalgia. https://www.nytimes.com/2025/01/12/magazine/chronic-pain.html?unlocked_article_code=1.ok4.Ggyl.jPE4qqT8991M&smid=url-share

Full title: Transcutaneous electrical nerve stimulation for fibromyalgia-like syndrome in patients with Long-COVID: a pilot randomized clinical trial Alejandro Zulbaran-Rojas, Rasha O. Bara, Myeounggon Lee, Miguel Bargas-Ochoa, Tina Phan, Manuel Pacheco, Areli Flores Camargo, Syed Murtaza...

Found this thread by Sabrina Porter on bluesky and though worth sharing. For rest see: https://bsky.app/profile/sabrinapoirier.bsky.social/post/3lcxcph4iec2l Thought she made some really good points. Except for the unproven mast cell and brain inflammation stuff at the end.

Background Chronic overlapping pain conditions (COPCs), pain-related conditions that frequently occur together, may occur in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to identify comorbid COPCs in patients with...

Abstract Study design: A cohort study with 12 months of follow-up. Objective: To assess (1) the unidimensionality of the Fear-Avoidance Beliefs Questionnaire (FABQ) and (2) whether single questions in the FABQ predict future sickness absence as well as the whole scale. Summary of background...

There have been several local news articles where chronic pain patients report improvement with a neurostimulation device that unfortunately costs tens of thousands of euros. Some ME/CFS patients with chronic pain have asked about this too. Does anyone have experience with it or is anyone...

C-Reactive Protein (CRP) is Associated With Chronic Pain Independently of Biopsychosocial Factors The Journal of Pain Pre-print: https://pubmed.ncbi.nlm.nih.gov/37741522/ (Paragraphs added for legibility) Inflammation is linked with chronic pain but the extent to which this relationship is...

Identification and targeting of a unique NaV1.7 domain driving chronic pain Gomez, Kimberly; Stratton, Harrison J.; Duran, Paz; Loya, Santiago; Tang, Cheng; Calderon-Rivera, Aida; François-Moutal, Liberty; Khanna, May; Madura, Cynthia L.; Luo, Shizhen; McKiver, Bryan; Choi, Edward; Ran, Dongzhi...

ABSTRACT Objective Chronic fatigue syndrome (CFS) is a debilitating illness characterized by persistent fatigue among other symptoms. Pain symptoms are common and included in the diagnostic criteria for CFS but are not required for diagnosis. Despite the association between CFS and pain, few...

Abstract Background Neurostimulation is a highly effective therapy for the treatment of chronic Intractable pain, however, due to the complexity of pain, measuring a subject’s long-term response to the therapy remains difficult. Frequent measurement of patient-reported outcomes (PROs) to reflect...

Abstract Neuropathic pain is a debilitating condition affecting around 8% of the adult population in the UK. The pathophysiology is complex and involves a wide range of processes, including alteration of neuronal excitability and synaptic transmission, dysregulated intracellular signalling and...

Abstract Chronic pain syndromes are often refractory to treatment and cause substantial suffering and disability. Pain severity is often measured through subjective report, while objective biomarkers that may guide diagnosis and treatment are lacking. Also, which brain activity underlies chronic...

Abstract Objectives The objective of the present study was to test the moderating impact of an unknown pain etiology on the relationship between psychological factors and chronic pain intensity and disability. Methods N = 471 chronic pain sufferers presented to an online Cognitive Behavioral...

Integrative miRNA–mRNA profiling of human epidermis: unique signature of SCN9A painful neuropathy Andelic, Mirna; Salvi, Erika; Marcuzzo, Stefania; Marchi, Margherita; Lombardi, Raffaella; Cartelli, Daniele; Cazzato, Daniele; Mehmeti, Elkadia; Gelemanovic, Andrea; Paolini, Matilde; Pardo...

Chronic pain - what therapy can help with https://www.bacp.co.uk/about-therapy/what-therapy-can-help-with/chronic-pain/

What has brain diffusion MRI taught us on chronic pain: a critical review Monica Sean, Graham Little, Paul Bautin, Marylie Martel, Maxime Descoteaux, Guillaume Leonard, Pascal Tetreault Chronic pain is a widespread health condition affecting millions of individuals worldwide. Despite its high...

Here is the email I received from Younger's Lab this morning: f you’ve ever taken a psychedelic substance, and you have chronic pain, we’d love to hear more about your experience. We are conducting a brief online survey to learn more about the relationship between chronic pain and classic...

ABSTRACT Background Fibromyalgia (FM) is a diagnostically controversial syndrome characterized by chronic widespread pain, fatigue, sleep difficulties, cognitive dysfunction, and mental health symptoms. Though online peer support groups (OPSGs) may help persons with FM access support and...