A research perspective on sphingolipid metabolism and myalgic encephalomyelitis/chronic fatigue syndrome
Xiao, Junhua
No abstract.
Link | PDF (Neural Regeneration Research)
Integrative Multi-Omics Framework for Causal Gene Discovery in Long COVID
Thuc Duy Le, Sindy Licette Pinero, Xiaomei Li, Lin Liu, Jiuyong Li, Sang Hong Lee, Marnie Winter, Thin Nguyen, Junpeng Zhang
Background
Long COVID, or Post–Acute Sequelae of COVID–19 (PASC), involves persistent...
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens
Neu, Frieder; Nay, Sandra; Schuchardt, Sven; Klawonn, Frank; Skripuletz, Thomas; Suehs, Kurt-Wolfram...
Metabolic network analysis of pre-ASD newborns and 5-year-old children with autism spectrum disorder
Lingampelly, Sai Sachin; Naviaux, Jane C.; Heuer, Luke S.; Monk, Jonathan M.; Li, Kefeng; Wang, Lin; Haapanen, Lori; Kelland, Chelsea A.; Van de Water, Judy; Naviaux, Robert K.
Classical...
Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach
Sara Martínez; Oihane E. Albóniga; María Rosa López-Huertas; Ana Gradillas; Coral Barbas
Despite the recent and increasing knowledge surrounding...
Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets
Gerhard Hagn; Samuel M. Meier-Menches; Günter Plessl-Walder; Gaurav Mitra; Thomas Mohr; Karin Preindl; Andreas Schlatter; Doreen Schmidl; Christopher Gerner; Gerhard Garhöfer; Andrea Bileck...
Sphingolipids and their metabolism in physiology and disease
Hannun, Yusuf A.; Obeid, Lina M.
Studies of bioactive lipids in general and sphingolipids in particular have intensified over the past several years, revealing an unprecedented and unanticipated complexity of the lipidome and its many...
Impact of sphingolipids on protein membrane trafficking
Aguilera-Romero; Lucena; Sabido-Bozo; Muñiz
Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination...
Full Title: Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 with and without POTS syndrome; a multi-omic profiling study, 2023, Ali Mahdi et al
Abstract
Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction, especially...
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants
Farley, Scotland E.; Kyle, Jennifer E.; Leier, Hans C.; Bramer, Lisa M.; Weinstein, Jules B.; Bates, Timothy A.; Lee, Joon-Yong; Metz, Thomas O.; Schultz, Carsten; Tafesse, Fikadu G.
A comprehensive...
Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response
Hyun-Eui Kim; Ana Rodrigues Grant; Milos S. Simic; Rebecca A. Kohnz; Daniel K. Nomura; Jenni Durieux; Celine E. Riera; Melissa Sanchez; Erik Kapernick; Suzanne Wolff; Andrew Dillin
Summary
Defects in mitochondrial...
Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis
Jeson J Li; Nan Xin; Chunxia Yang; Larrisa A Tavizon; Ruth Hong; Travis I Moore; Rebecca G Tharyan; Adam Antebi; Hyun-Eui Kim
Maintaining protein homeostasis is essential...
Immunometabolic rewiring in long COVID patients with chronic headache
Suan-Sin Foo, Weiqiang Chen, Kyle L Jung, Tamiris Azamor, Un Yung Choi, Pengfei Zhang, Suzy AA Comhair, Serpil C Erzurum, Lara Jehi, Jae U Jung
Almost 20% of patients with COVID-19 experience long-term effects, known as...
This is the latest work of Dr Naviaux and colleagues on cell-danger response, on mice.
Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder
Abstract
Since 2012, studies in mice, rats, and humans have suggested...
Full title: Multiple Sclerosis: Melatonin, Orexin, and Ceramide Interact with Platelet Activation Coagulation Factors and Gut-Microbiome-Derived Butyrate in the Circadian Dysregulation of Mitochondria in Glia and Immune Cells
Open access, https://www.mdpi.com/1422-0067/20/21/5500/htm
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