Abstract
Cerebral blood flow (CBF) is vital for delivering oxygen and nutrients to the brain. Many forms of orthostatic intolerance (OI) involve impaired regulation of CBF in the upright posture, which results in disabling symptoms that decrease quality of life.
Because CBF is not easy to...
Respiratory influence on cerebral blood flow and blood volume – A 4D flow MRI study
Pontus Söderström; Anders Eklund; Nina Karalija; Britt M Andersson; Katrine Riklund; Lars Bäckman; Jan Malm; Anders Wåhlin
Variations in cerebral blood flow and blood volume interact with intracranial pressure...
Dietary sodium and health: How much is too much for those with orthostatic disorders?
Stock; Chelimsky; Edwards; Farquhar
High dietary salt (NaCl) increases blood pressure (BP) and can adversely impact multiple target organs including the vasculature, heart, kidneys, brain, autonomic nervous...
Highlights
POTS causes cardiovascular instability and severe symptoms.
Postural hyperventilation is thought to cause POTS, but the mechanisms are unclear.
Reduced stroke volume and brain perfusion drive postural hyperventilation in POTS.
Stroke volume and brain perfusion should be targeted as...
Cardiac Origins of the Postural Orthostatic Tachycardia Syndrome
Fu; VanGundy; Galbreath; Shibata; Jain; Hastings; Bhella; Levine
Objectives
The purpose of this study was to test the hypothesis that a small heart coupled with reduced blood volume contributes to the postural orthostatic...
Renin-Aldosterone Paradox and Perturbed Blood Volume Regulation Underlying Postural Tachycardia Syndrome
Satish R. Raj; Italo Biaggioni; Paula C. Yamhure; Bonnie K. Black; Sachin Y. Paranjape; Daniel W. Byrne; David Robertson
Background
Patients with postural tachycardia syndrome (POTS)...
https://portlandpress.com/clinsci/article-abstract/118/2/125/68670
Scihub
2010 paper
Barry Hurwitz; Virginia Coryell; Meela Parker; Pedro Martin; Arthur LaPerriere; Nancy Klimas; George Sfakianakis; Martin Bilsker
Abstract
The study examined whether deficits in cardiac output and blood volume...
This post and others on the thread have been copied or moved from this thread on MEAction Research Summary 2019
One example: The ME Action research summary suggests that a reduced blood volume has repeatedly been found. That seems to contrast with how the latest study on this topic summarized...
Frontiers in Pediatrics: Blood volume status in CFS/ME correlates with the presence or absence of orthostatic symptoms
Introduction: Conflicting data have been published on the reduction of circulating blood volume in adults with Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The...
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