atg13

  1. forestglip

    Trial Report Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy, 2025, Ruan et al

    Low Dose Rapamycin Alleviates Clinical Symptoms of Fatigue and PEM in ME/CFS Patients via Improvement of Autophagy Brian T. Ruan, Sarojini Bulbule, Amy Reyes, Bela Chheda, Lucinda Bateman, Jennifer Bell, Braydon Yellman, Stephanie Grach, Jon Berner, Daniel L. Peterson, David Kaufman, Avik Roy...
    • forestglip
    • Thread
    • atg13 autophagy beclin-1 me/cfs mtor pser258-atg13 rapamycin
    • Replies: 18
    • Forum: ME/CFS research
  2. InitialConditions

    Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle‑serving nerves and spinal cord, 2025, Drosen et al.

    Abstract Chronic muscle fatigue is a condition characterized by debilitating muscle weakness and pain. Based on our recent finding to study the potential effect of mTOR on ATG13 inactivation in chronic muscle fatigue, we report that biweekly oral administration with MHY1485, a potent inducer of...
  3. SNT Gatchaman

    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA, 2023, Wang et al.

    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA Wang, Yufen; Que, Huilin; Li, ChuangPeng; Wu, Zhe; Jian, Fenglei; Zhao, Yuan; Tang, Haohao; Chen, Yang; Gao, Shuaixin; Wong, Catherine C.L.; Li, Ying; Zhao, Chongchong; Rong, Yueguang Autophagy is a conserved and tightly...
  4. belbyr

    mTOR activation, ATG13 inactivation and suppression of autophagy

    Split from USA: NIH National Institutes of Health news Avik Roy and Gunnar Gottschalk presented their hypothesis on a NIH ME/CFS working Group call A relevant paper is Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al...
  5. J

    Simmaron’s Dr. Avik Roy has won an NIH R21 grant for “ATG13: A new player in MECFS.” April 2023

    Posts moved from this thread: Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al _______________ From email: Simmaron Research Wins our 1st NIH Grant! We are proud to announce our very own Dr. Avik Roy PhD and Dr. Gunnar...
  6. SNT Gatchaman

    Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy, Puente et al, 2016

    Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy Cindy Puente, Ronald C Hendrickson, Xuejun Jiang Abstract Autophagy is a conserved catabolic process that utilizes a defined series of membrane trafficking events to generate a de novo double-membrane vesicle...
  7. Sly Saint

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    For the abstract of the published paper, go to post #9 Preprint Abstract Myalgic Encephalomyelitis and chronic fatigue syndrome is a multisystem illness characterized with extreme muscle fatigue associated with pain, neurocognitive impairment, and chronic inflammation. Despite intense...
    • Sly Saint
    • Thread
    • alpha-synuclein atg13 autophagy avik roy blood gottschalk me/cfs microglia nitric oxide simmaron something in the blood
    • Replies: 72
    • Forum: ME/CFS research
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