2024

  1. ME/CFS Skeptic

    What are the most interesting ME/CFS-studies of 2024?

    We've written a blog post highlighting the most interesting ME/CFS studies of 2024: https://mecfsskeptic.com/2024-looking-back-on-a-year-of-me-cfs-research/ Curious to know if we missed any important ones. Twitter/Bluesky summary here:
  2. Wyva

    Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank, 2024, Huang et al

    Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher & Christopher W. Armstrong Abstract Background Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and...
  3. Wyva

    High prevalence of LC in anti-TPO positive euthyroid individuals with strongly elevated SARS-CoV-2-specific T cell responses (...), 2024, Matula et al

    Full title: High prevalence of long COVID in anti-TPO positive euthyroid individuals with strongly elevated SARS-CoV-2-specific T cell responses and moderately raised anti-spike IgG levels 23 months post-infection Zsolt Matula1 Viktória Király2 Gabriella Bekő2 Márton Gönczi2 András Zóka2 Róbert...
  4. Wyva

    Barriers and facilitators of healthcare access for LC patients in a universal healthcare system: qualitative evidence from Austria, 2024, Gamillscheg

    Full title: Barriers and facilitators of healthcare access for long COVID-19 patients in a universal healthcare system: qualitative evidence from Austria Peter Gamillscheg, Agata Łaszewska, Stefanie Kirchner, Kathryn Hoffmann, Judit Simon & Susanne Mayer Abstract Background Long COVID-19...
  5. J

    Impacts of the 2024 change in US government on ME/CFS and Long Covid

    Moderation note: Please note the title of the thread and keep on-topic. Restrict your posting to information that is highly relevant to ME/CFS and Long Covid. Consider our rules, particularly this part of Rule 11, before posting: ******* Not good. https://wapo.st/3UEZWaZ Florida surgeon...
  6. Wyva

    Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing, 2024, Sun et al

    Abstract The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) was used to...
  7. Wyva

    Review Chronic Fatigue Syndrome: Diagnosis, Treatment, and Future Direction, 2024, Graves et al

    B. Sue Graves • Mitsu Patel • Hailey Newgent • Gauri Parvathy • Ahmad Nasri • Jillene Moxam • Gurnoor S. Gill • Vivek Sawhney • Manish Gupta Abstract Myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a complex, chronic condition marked by persistent, debilitating...
  8. Wyva

    Resting-state neural dynamics changes in older adults with post-COVID syndrome and the modulatory effect of cognitive training and sex, 2024, Nagy et

    Boglárka Nagy Andrea B. Protzner, Balázs Czigler & Zsófia Anna Gaál Abstract Post-COVID syndrome manifests with numerous neurological and cognitive symptoms, the precise origins of which are still not fully understood. As females and older adults are more susceptible to developing this...
  9. Wyva

    Long COVID diagnostic with differentiation from chronic lyme disease using machine learning and cytokine hubs, 2024, Patterson et al

    Bruce K. Patterson, Jose Guevara-Coto, Javier Mora, Edgar B. Francisco, Ram Yogendra, Rodrigo A. Mora-Rodríguez, Christopher Beaty, Gwyneth Lemaster, Gary Kaplan DO, Amiram Katz & Joseph A. Bellanti Abstract The absence of a long COVID (LC) or post-acute sequelae of COVID-19 (PASC)...
  10. Wyva

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After SARS-CoV-2 Infection, 2024, Unger et al

    Key Points Question Does prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)–like illness differ between individuals with an acute infection–like index illness who are COVID-19 positive or negative? Findings In this cohort study of 4378 participants, the weighted...
  11. Wyva

    Review Post-acute sequelae of SARS-CoV-2 infection (Long COVID) in older adults, 2024, Russell et al

    Samantha J. Russell, Karen Parker, Andrea Lehoczki, David Lieberman, Indu S. Partha, Serena J. Scott, Linda R. Phillips, Mindy J. Fain & Janko Ž. Nikolich Abstract Long COVID, also known as PASC (post-acute sequelae of SARS-CoV-2), is a complex infection-associated chronic condition...
  12. Wyva

    The impact of the COVID-19 pandemic on the psychosomatic status of emeritus professors: The importance of active lifestyles, 2024, Takács et al

    Abstract Purpose The COVID-19 pandemic has had an enormous negative impact on the psychosomatic status of the general population, and especially of more vulnerable populations, such as older people. The present study aimed to assess changes in psychosomatic status before and after the COVID-19...
  13. Hoopoe

    Protocol Faecal microbiota transplantation (FMT) in Norwegian outpatients with mild to severe ME/CFS: protocol (...), 2024, Skjevling et al. Comeback Study

    Some details are now know. I'm not happy about Chalder fatigue scale being used as primary outcome. https://clinicaltrials.gov/ct2/show/NCT03691987
  14. Wyva

    Psychiatric adverse events following COVID-19 vaccination: a population-based cohort study in Seoul, South Korea, 2024, Kim et al

    Abstract Evidence has suggested an increased risk of psychiatric manifestations following viral infections including coronavirus disease-2019 (COVID-19). However, psychiatric adverse events (AEs) after COVID-19 vaccination, which were documented in case reports and case series, remain unclear...
  15. Wyva

    Review Cognitive impairment in long-COVID, 2024, Tozkir et al

    Background – Long Covid is a complex condition characterised by symptoms that persist for weeks and months after the Covid infection, accompanied by cognitive impairment that negatively affects daily life. Understanding this complex condition is important for the development of diagnostic and...
  16. Trish

    UK Invest in ME Research conference, June 2024

    The 16th Invest in ME Research International ME Conference 2024 28 June 2024 Wellcome Genome Campus, UK #IIMEC16 Advancing Understanding of ME: Bridging Research and Clinical Treatment https://www.investinme.org/IIMEC16.shtml Programme IIMEC16 CONFERENCE AGENDA - 28 JUNE 2024 The...
  17. Wyva

    Trial Report Optimizing cardiopulmonary rehabilitation duration for long COVID patients: an exercise physiology monitoring approach, 2024, Szarvas et al

    Abstract The presence of prolonged symptoms after COVID infection worsens the workability and quality of life. 200 adults with long COVID syndrome were enrolled after medical, physical, and mental screening, and were divided into two groups based on their performance. The intervention group...
  18. Wyva

    Higher level of physical activity reduces mental and neurological symptoms during and 2 years after COVID-19 infection in young women, 2024, Takács et

    Abstract Previous studies found that regular physical activity (PA) can lower the risk of SARS-CoV-2 (COVID-19) infection and post-COVID-19 condition (PCC), yet its specific effects in young women have not yet been investigated. Thus, we aimed to examine whether regular physical activity...
  19. Wyva

    Fatigue and symptom-based clusters in post COVID-19 patients: a multicentre, prospective, observational cohort study, 2024, Cornelissen et al

    Abstract Background In the Netherlands, the prevalence of post COVID-19 condition is estimated at 12.7% at 90–150 days after SARS-CoV-2 infection. This study aimed to determine the occurrence of fatigue and other symptoms, to assess how many patients meet the Myalgic Encephalomyelitis/Chronic...
  20. Wyva

    Estimates of Incidence and Predictors of Fatiguing Illness after SARS-CoV-2 Infection, 2023, Vu, Unger et al

    Abstract This study aimed to estimate the incidence rates of post–COVID-19 fatigue and chronic fatigue and to quantify the additional incident fatigue caused by COVID-19. We analyzed electronic health records data of 4,589 patients with confirmed COVID-19 during February 2020–February 2021 who...
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