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How a long COVID rehabilitation intervention works: refining its programme theory through a realist-informed qualitative study BACKGROUND Although the majority of individuals infected with SARS-CoV-2 recover without treatment, some individuals experience persistent symptoms (long COVID), which...

Sigh.

Cognitive behavioral therapy, exercise training, and cognitive remediation for patients with post-COVID-19 condition: protocol of an open-label randomized controlled trial BACKGROUND Effective rehabilitation programs targeting transdiagnostic mechanisms of persistent physical symptoms are...

MTHFR allele and one-carbon metabolic profile predict severity of COVID-19 While the public health burden of SARS-CoV-2 infection has lessened due to natural and vaccine-acquired immunity, emergence of less virulent variants, and antiviral medications, COVID-19 continues to take a significant...

Prospective Associations of Long COVID with Sleep Health Nearly 3 Years After SARS-CoV-2 Infection: A Statewide Representative Cohort Study STUDY OBJECTIVES While many adults with Long COVID experience sleep problems, the long-term relationship between Long COVID and sleep remains poorly...

It may not to patients but it will to doctors. No end to the iterations with coded language — with plausible deniability.

It's had an update https://www.ncbi.nlm.nih.gov/books/NBK557676/ Looks muddled and contradictory. They'd do better linking our factsheets. Eg Also Would be nice…

Durability, fatigability, repeatability, and resilience in endurance sports: definitions, distinctions, and implications (2025, Journal of Applied Physiology)

FATIGABILITY Definition and Empirical Evidence Fatigue represents a critical constraint in human performance, operationally defined as “an acute impairment of performance that includes both an increase in the perceived effort necessary to exert a desired force and an eventual inability to...

Durability, fatigability, repeatability, and resilience in endurance sports: definitions, distinctions, and implications Web | DOI | PDF | Journal of Applied Physiology | Open Access Prompted 7 letters and a reply.

HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity Type 1 narcolepsy (T1N), an autoimmune disease associated with a disruption of hypocretin/orexin neurons, has conserved genetic effects transcending cultures and ethnicities. We pooled data...

I think that's probably technical, not nefarious. The canonical URL in the metadata includes the port number 5037 which is very odd. It is also inaccessible, at least externally, so this may just be temporary staging server links and things haven't quite coalesced into their final form...

This entire body of literature may have to be thrown out. Lazily copy-pasting the Google AI description — From BOLD signal changes can oppose oxygen metabolism across the human cortex (2025) —

https://www.bundestag.de/dokumente/textarchiv/2025/kw51-pa-forschung-1129458 According to this Reddit thread — which was said in comments to likely refer to the anti-CD38 mAb isatuximab. (Previous Sanofi PR for myeloma)

Published as — Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry SARS-CoV-2 infection can result in long COVID, characterized by post-acute symptoms from multiple organs. Current hypotheses on mechanisms underlying long COVID...

Canadian Consensus Criteria vs healthy (not sedentary) controls.

Prior papers from this group came in for criticism, esp the 2022 one. This paper looks to be of better quality and reads pretty clearly. Could the kynurenine pathway be the key missing piece of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ME/CFS complex puzzle? (2022) Dysregulation of...