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I'm in my 70s too and I don't see this as an issue of old school manners, to be honest. Members here are critical of the scientific methodology, as they should be. I have seen no hostility. Not a hint of 'personal attacks'. And this forum is not 'social media'. It is a science forum. We have...

How about taking away the therapist?

Fascinating. Keep at it.

Maybe tell that to Mr Shiozaki.

Well, Mayo seems to put out all sorts of guff these days. In the days when I was involved in setting exam questions relating to osteoporosis pathways exercises were not on the list. That just looks like a trotting out of the 21st century mantra that exercise is great for everything.

But presumably a failure to distinguish is only relevant if some form of exercise is relevant, and there is no reason to think it is. And it is a bit confusing because I doubt those recommending exercise had any interest in endothelium either way. I don't see any evidence base for this theory so...

This is what worries me. I was doing inflammation research when these people were in kindergarten or not yet born. If there is an infiltrate of cells going through the vessel wall into the tissue that is inflammation of that tissue, as in myositis. If the infiltrate is merely into the layers of...

I think a lot of physicians would agree to the fact that we have no reliable evidence base for most physio. That does not necessarily mean that they do not use physio services. Doctors are not always good at sticking to what they know t be reliable evidence! Physiotherapists may have a useful...

What is endothelialitis @YiannisK ? I spent my career in inflammation research and have never heard of it. All I can see in the abstract is some rather stretched out speculations. As far as I can work out there is no point in trying to get people with Long Covid or ME/CFS to do exercises of any...

Indeed. In fact 'Long Covid' is a typical example of the muddled thinking behind traditional 'diagnosis'.

Doesn't seem to be very novel!

+2 Exercises have never been part of the recommendation for osteoporosis as far as I know. If you have osteoporosis and do a lot of exercises you will probably increase the risk of breaking things. Keeping thin actually makes osteoporosis worse. It makes sense that keeping reasonably active...

Almost all treatment provided by physiotherapists is not based on reliable evidence. There are a few areas where there are a few useful trials that allow some meaningful conclusions to be drawn but even then a lot of questions tend to remain. The norm is that physiotherapists have no...

It happens sometimes.

It is bizarre that people who claim to have expertise in psychology have no insight into the spsychology of this. Of course the open placebo will do well, because that was the point of the trial - to show that open placebos do well, and subjects don't like to disappoint their nice psychologist...

Too many unknowns to answer that usefully.

If there is involverment of the British Psychological Society could a formal complaint be made?

I actually think this might be a good thing. Whoever they ask will have to find out what it is all about. There will be no actual tests to do because these are common SNP variants. So both the physician and the patient may learn something. An intelligent physician would say 'no we don't yet...

I think this demonstrates how difficult it is to try to get this absolutely right with language for a general audience. This version is probably less right! Maybe something like: The DecodeME study, published in 2025, demonstrated that variants of certain DNA regions, some linked to genes...

I suspect that studies of 'Long Covid' based on questionnaires like this are pretty meaningless. There are all sorts of confounding reasons why hypertension might have a negative association.