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  1. Slamdancin
    Post

    Trial Report Low Vasopressin in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2024, Huhmar/Bragée/Polo

    “Dietary sodium may stimulate vasopressin secretion through extracellular osmolality or even by a direct effect of extracellular sodium on...
    Post by: Slamdancin, Apr 14, 2024 in forum: ME/CFS research
  2. Slamdancin
    Post

    Trial Report Low Vasopressin in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2024, Huhmar/Bragée/Polo

    Could it be helpful to take some salt first thing in the morning? https://www.sciencedirect.com/science/article/pii/S2211124721001807...
    Post by: Slamdancin, Apr 14, 2024 in forum: ME/CFS research
  3. Slamdancin
    Post

    Trial Report Imbalanced Brain Neurochemicals in long COVID and ME/CFS: A Preliminary Study using MRI, 2024, Thapaliya et al

    Glutamate also increases cerebral blood flow which might be a compensatory mechanism that when working can keep a pwME in the more mild categories.
    Post by: Slamdancin, Apr 10, 2024 in forum: ME/CFS research
  4. Slamdancin
    Post

    Trial Report Imbalanced Brain Neurochemicals in long COVID and ME/CFS: A Preliminary Study using MRI, 2024, Thapaliya et al

    Could this be a clue as to why benzodiazepines seem to increase capacity/functionality acutely? This is anecdotal of course but it seems to at...
    Post by: Slamdancin, Apr 8, 2024 in forum: ME/CFS research
  5. Slamdancin
    Post

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    Quick search of the literature found that this gene is HIF-1a and hypoxia activated in cancer cells
    Post by: Slamdancin, Sep 17, 2022 in forum: ME/CFS research
  6. Slamdancin
    Post

    Neurovascular Dysregulation and Acute Exercise Intolerance in ME/CFS: A Randomized, Placebo-Controlled Trial of Pyridostigmine, 2022, Systrom et al

    Unfortunately Mestinon never helped me all that much in the past. Maybe it’s worth another shot though
    Post by: Slamdancin, May 6, 2022 in forum: ME/CFS research
  7. Slamdancin
    Post

    Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy, Puente et al, 2016

    https://pubmed.ncbi.nlm.nih.gov/27973551/ Rapamycin dephosphorylates ATG13 on paper but didn’t help me
    Post by: Slamdancin, Apr 29, 2022 in forum: Other health news and research
  8. Slamdancin
    Post

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    From one paper I read in a quick Google search mTorC1 is directly upstream of p-ATG13
    Post by: Slamdancin, Apr 28, 2022 in forum: ME/CFS research
  9. Slamdancin
    Post

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    Just wanted to add that I tried Rapamycin for a few months a couple years ago and even though it never helped I stuck with it because some of us...
    Post by: Slamdancin, Apr 28, 2022 in forum: ME/CFS research
  10. Slamdancin
    Post

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714170/ ATG13 has non-autophagic capabilities and it appears to be anti-viral and relate to...
    Post by: Slamdancin, Apr 27, 2022 in forum: ME/CFS research
  11. Slamdancin
    Post

    Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients, Bertinat et al (2022)

    @SNT Gatchaman They say it’s unexpected but I have seen eNOS come up at least once in the ME literature. This is a novel mechanism though. I’m...
    Post by: Slamdancin, Jan 21, 2022 in forum: ME/CFS research
  12. Slamdancin
    Post

    Metabolomic Evidence for Peroxisomal Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2022, Levine,Hornig,Lipkin et al

    @mariovitali
    Post by: Slamdancin, Jan 12, 2022 in forum: ME/CFS research
  13. Slamdancin
    Post

    The micro-clot finding in Long Covid — implications for the possible aetiology of ME/CFS

    @JES I had almost the exact same reaction to NatTokinase/Bromelain. A hopeful start but definitely worse after a few days. The flu like symptoms...
    Post by: Slamdancin, Nov 11, 2021 in forum: Blood (e.g. coagulation, cell stiffness)
  14. Slamdancin
    Post

    United Kingdom: Sheffield ME & Fibromyalgia Group News

    New to me was the findings of high phenylalanine and low BH4. Ron also said they have other indications of low dopamine. Going to add Vitamin...
    Post by: Slamdancin, Oct 13, 2021 in forum: News from organisations
  15. Slamdancin
    Post

    Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function, 2019, Greenburg et al

    Are you hinting at a compound you know of? I’d be quite interested in taking a look at such a thing.
    Post by: Slamdancin, Jun 18, 2019 in forum: Other health news and research
  16. Slamdancin
    Post

    Multidisciplinary Biopsychosocial Program for Chronic Musculoskeletal Pain at the Dead Sea, 2019, Dramsdahl et al

    This is extremely interesting to me as hot baths and heating pads, along with ice alternatively, seem to allow my body to accept some help energy...
    Post by: Slamdancin, May 4, 2019 in forum: Other psychosomatic news and research
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