It amazes me that people believe that Covid, which killed over 7 million people worldwide, can kill you but if it doesn't then it can only leave you 100% healthy i.e. that Long Covid doesn't exist.
Full title: Fatigue, Interoplastic and Nociplastic Distress in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, Gulf War Illness and Chronic Idiopathic Fatigue
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2025.1530652/abstract
Myalgic Encephalomyelitis /...
Now published
Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) entails low quality of life for patients and massive societal costs. There is an urgent need for elucidation of disease mechanisms and for rational treatment. Our working hypothesis is that ME/CFS in a...
Abstract
While post-infectious (PI-ME/CFS) and gradual onset (GO-ME/CFS) myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) manifest similar symptoms, it has long been suspected that different disease processes underlie them.
However, the lack of biological evidence has left this...
https://www.preprints.org/manuscript/202507.0058/v1
Abstract
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating, multi-system disease characterized by profound fatigue, post-exertional malaise (PEM), and a constellation of immune, neurological, and autonomic symptoms...
Full title:
Immune Signatures in Post-Acute Sequelae of COVID-19 (PASC) and Myalgia/Chronic Fatigue Syndrome (ME/CFS): Insights from the Fecal Microbiome and Serum Cytokine Profiles
Abstract
While there are many postulates for the etiology of post-viral chronic fatigue and other...
https://www.preprints.org/manuscript/202506.2016/v1
Abstract
Fatigue is the most common symptom of Long-COVID (LC), characterized by persistent or new symptoms occurring at least three months after the initial SARS-CoV-2 infection, with no other identifiable cause.
This study aims to assess the...
Pilot Study published
https://www.s4me.info/threads/plasma-cell-targeting-with-the-anti-cd38-antibody-daratumumab-in-me-cfs-a-clinical-pilot-study-2025-fluge-et-al.44736/#post-618982
Thread on the proposed full trial
https://www.s4me.info/threads/norway-plasma-cell-aimed-treatment-with-daratumumab-in-me-cfs-haukeland-university-hospital.44450/
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1607353/abstract
Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) entails low quality of life for patients and massive societal costs. There is an urgent need for elucidation of disease mechanisms...
https://www.bbc.co.uk/news/articles/cy8k73443g4o
Chronic fatigue is not in your head, it's in your blood - experts
People with ME - or chronic fatigue syndrome - have major differences in their blood compared with healthy individuals, experts have found.
University of Edinburgh researchers...
Abstract
The underlying pathologies driving post-acute infectious syndromes (e.g. myalgic encephalomyelitis / chronic fatigue syndrome, long COVID, etc) remain poorly understood. Given the extreme burden these illnesses impose on suffers, and the dramatic increase in cases following the COVID-19...
Henrique Chapola, Sissel Elisabeth Furesund Dyrstad, Karl Johan Tronstad are co-authors in this recent thread
https://www.s4me.info/threads/charting-the-circulating-proteome-in-me-cfs-cross-system-profiling-and-mechanistic-insights-2025-hoel-fluge-mella.44410/#post-613425
https://www.bbc.co.uk/news/articles/cgr5lej9l8lo
The first bacteria our bodies meet – in the hours after we're born – could protect us from dangerous infections, UK scientists say.
They have shown, for the first time, that good bacteria seem to halve the risk of young children being admitted...
This is the same for me also. I think this is very common in people with ME.
When I first got ill and was still working and was trying to explain my symptons of fatigue to disbelieving people, "so what, we all get tired!", it was only when I mentioned that I felt exhausted in the morning and...
Full title:
Evaluating Pacing Therapy (PT) versus Graded Exercise Therapy (GET) for improving fatigue, pain, and quality of life in adults with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Systematic Review...
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