https://www.nejm.org/doi/full/10.1056/NEJMc2403705 A new study showing scl70 can continue go down if cd19 car T cells sustained longer. Also...
Ah thank you. That's good to know. Is the Luminary BAFF including all three? Question: I was checking Novartis ELIANA trial and found out that...
Thank you Dr. Edwards. I attached a figure from Dr. Schett's review. However, after reading your comments on ritux depleting plasmablasts, I...
Sorry I did not know that. Well, you are right- this does not look as miraculous. It might be similar to Tafasitamab. The only hope is to see if...
The prerequisite for CD19 to give you relief is that the disease causing antibodies, at least part of which, are coming from plasmablasts. If they...
Thank you. It is a bad news to hear that maybe SSA is sufficient to trigger nephritis relapse. But at least we know which direction to work on....
Rituximab does not target plasmablasts which probably account for the Anti-Smith. Given the disappearance of that by CD19 CAR T, I think it is not...
Thank you for educating me on that. I agree. Some RA patients, especially seronegative ones, may not be responsive to CAR T if the pathology is...
This is definitely exciting and critical study to initiate the efforts to treat RA with deep depletion of B cells. However, one must be cautious...
Dr. Thomas the lupus encyclopedia doctor heard one of Dr. Schett's patient's SLE relapsed (not verified)- have you heard anything about it?
May I ask are you sure 1 Schett's SLE patient's RA is treated well with CAR T CD19? I did not see it in his publication. Maybe I did not read it...
Gracell is now part of AstraZeneca. Don't know how it is going to affect their strategy. For you, I think it remains a question how much your SSA...
Which report did you see? I saw there were 2 progressive MS patients received CAR T in March and it is too early to assess efficacy. Another...
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