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  1. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I wish I could join. What little mental capacity I have is being overused to keep up with paperwork for SSDI (our disability benefits). just saying hello & checking in to catch up. but can’t even comprehend much today! Hope you all are doing well!!!
  2. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Thanks for submitting these, Andrew. Re: Walitt's response, I don't recall whether there was precedent for using number of hard choices versus using difference in motivation effect. Does someone recall? Also there is a teleconference May 6. Does anyone know if they've been asked about whether...
  3. JoClaire

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Agree gender seems as if it’d be important and add noise. See link to Hutan in above link comment. @andrewkq was able to map the data sets The data for the grip graphs doesn’t include gender, age, etc.
  4. JoClaire

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Thx for sharing. I'm still in PEM and digesting. But curious how you were able to connect the grip data to the PHTC data.
  5. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Thanks, Andrew. I've been out for a few weeks myself. Appreciate you using your energy on the letter and sharing your thoughts. I'm curious if there are plans for this? Also if we will ask our key question at the symposium or reserve it for when we share the letter.
  6. JoClaire

    Psychological flexibility in somatic symptom and related disorders: A case control study 2024 Selker et al

    What do we do with these campaigns? They are pathologizing taking a non neutral perspective on bodily sensations. I take a non neutral stance on this paper, fully mindful of the appropriate intensity of my emotion. Particularly hilarious is the use of the word “control” in the title. In...
  7. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I have not read published responses in nature. And don’t have a strategy for what would be most impactful. His argument centers around attributing differences to “error preference” (and “pacing”) and (ahem) “demonstrating” no difference in fatigue. Modeling hard tasks chosen over time (or...
  8. JoClaire

    Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I’m curious if one of the values @andrewkq has evaluated more strongly correlates with this. Agree. Gender, age, etc. are not given for these in raw data. And even in the first grip test, even if the groups are well matched, the variance due to gender, age differences within the groups...
  9. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Would you share results of Kendall’s tau? (No need for graph.) Did short refresher today and will try again later this week, depending on rest. Both of these methods first rank the values (PHTC and completion rate) and compare the ranked values to calculate the tau. Kendall’s analysis is more...
  10. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    That’s awesome. Damn distribution assumptions… Curious if you included any data from the Trials -4 through -1. I may have missed conversations about the practice trials. So apologies if I’m being redundant. Depending on how practice was run they may have meaningful information on PHTC. But I’d...
  11. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I think this could strengthen your argument if positioned in such a way. If PHTC shows effort preference, which (ahem) is “avoiding feelings of fatigue.” That should be strongly correlated with reported disability. Rather, percent complete is more closely tied to disability. The fact that...
  12. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    There are a number of things that add up for me. So fish smell still lingers. The patient variable is the least significant of other variables in the model you created. I suspect using a logarithmic variable for time, and an (logarithmic) interaction between time and patient (maybe gender) may...
  13. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Thanks for sharing Binkie. This type of *directed* practice process is not described in NIH paper. (No practice is described at all.- Not that I can find.) Nor does the data reflect this direction. Rather, it looks like the participant was free to choose during the early trials. (See notes and...
  14. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Thanks. This is really helpful. I hope to wind down to get good sleep tonight. Tomorrow, I hope to be able to share some of what I looked at yesterday and today. (Do you cross fingers or knock on wood in Belgium? Or something else for good luck? Does it help with brain fog?)
  15. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    This was my thinking too. Also do not have experience. ps I've been frustrated that I can't follow a thread (within this thread) from beginning to end. Just realized you can search for the post number (I just searched for <whatever the number was to @Dakota15's comment> & found ME/CFS Skeptic's...
  16. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Where did we find out the Walitt test was 15 minutes? (Edited this part: I am looking at data (3a). Totaling choice_time and completion_time seems a reasonable approximation of test duration. I am still suspicious about the one point in time. There are other reasons I just can't get them down...
  17. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    I noticed later your model structure was different than theirs. Let me know if it's not clear.
  18. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Yep. Filtering bug or user error. thanks!
  19. JoClaire

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    Facepalm. My bad. I double checked my filtering, but on reopening, data reappears. (The error was between the screen and the chair.) I'll go with my inner wisdom and rest now!!!
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