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Yes, plasmablasts go to the bone marrow to commit to plasma cell lineage, but they are also still found in some tissues. CD138 is highly expressed for LLPCs, but CD38 and BCMA have been chosen targets due to their still relatively high expression in LLPCs, but also coverage of plasmablasts /...

The patients who received CAR-T already failed Cyclophosphamide and the Fludarabine given is not a therapeutic dose. It's only to clear cells for CAR-T expansion. Also, anyone who says Rituximab and anti-CD19 CAR-T do the same thing, frankly have no idea what they're talking about. Btw, I am a...