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  1. rvallee

    Enhancing exercise intervention for patients with post-acute COVID-19 syndrome using mobile health technology: The COVIDReApp R..., 2024, Duenas et al

    Enhancing exercise intervention for patients with post-acute COVID-19 syndrome using mobile health technology: The COVIDReApp randomised controlled trial protocol https://journals.sagepub.com/doi/10.1177/20552076241247936 Abstract Objectives To analyse the effectiveness of a physical exercise...
  2. rvallee

    Network structure of functional somatic symptoms, 2024, Fischer et al

    If I understand this correctly, they did a bunch of graph math using questionnaires of symptoms, moods and other stuff, to find that people report those symptoms. So they basically identified the symptoms that patients report using a convoluted process. Somewhat. Genius stuff. The conclusion is...
  3. rvallee

    Network structure of functional somatic symptoms, 2024, Fischer et al

    Network structure of functional somatic symptoms https://www.sciencedirect.com/science/article/pii/S0022399924003805 Results The final network had a relatively small number of edges, with small (46.5 %) or small- to medium-sized (47.1 %) correlations. Ten communities were identified: and...
  4. rvallee

    ‘We need Psychologists… but please don’t psychologise Long Covid’

    ‘We need Psychologists… but please don’t psychologise Long Covid’ https://www.bps.org.uk/psychologist/we-need-psychologists-please-dont-psychologise-long-covid Interview with Dr David Joffe, a physician working with LC organizations, who seems like a good ally. I think it goes a bit far in...
  5. rvallee

    Guidance for best practice for clinical trials, World Health Organisation, 2024

    I wonder what's Cochrane's stance on this. "Just putting out there to look good, we don't intend and never meant to follow any of this"? It's for others? Even though basically no one will actually respect this, neither spirit nor word? What is good for, then? Just virtue signaling? Would it be...
  6. rvallee

    The UK Covid Inquiry - 2023 onward

    Seriously LC features heavily all throughout the inquiry. In many cases better and more realistically than most studies. Because it features the words of people who experience(d) it raw, unfiltered, without interpretation. Everyone with a chronic illness like LC or ME/CFS is considered...
  7. rvallee

    Guidance for best practice for clinical trials, World Health Organisation, 2024

    I can't find any other way to read this but "the standard in clinical practice is very low, so let's have the same standard in research". Of course it lowers costs. And of course it makes results closer to real-world, where a scientific approach is not possible. This is exactly what you don't...
  8. rvallee

    Guidance for best practice for clinical trials, World Health Organisation, 2024

    That's not what objective means. Doing this does not making an outcome objective, this is ridiculous. It can slightly lower the bias involved, but even then it only can do that, it does not mean that it will, and only slightly. Just the same way, let's imagine measuring the length of something...
  9. rvallee

    Medically not yet explained symptoms in hypothyroidism, 2024, Hegedüs et al.

    That's one interpretation. The symptoms are not yet understood by medicine, which is a fact. It's not a name, it's a descriptive sentence. Plugging in the tropey superfluous biopsychosocial nonsense is a choice that removes all meaning and value from it. It serves absolutely no purpose other...
  10. rvallee

    Anomalies in the review process and interpretation of the evidence in the NICE guideline for (CFS & ME), 2023, White et al

    Kind of reminds me of the budget jokes: Folks help me out is my monthly budget OK? Food: $300 Rent: $800 Utilities: $250 Loan on aircraft carrier: $2.6M Internet + mobile: $100 Misc, repairs, etc: $150 I think I need to cut back on Internet, but maybe I could eat less food, too? What do you...
  11. rvallee

    Hypothesis Long COVID as a functional somatic symptom disorder caused by abnormally precise prior expectations during Bayesian perceptual processing, 2023, Joffe

    Paul Garner tweeted this yesterday. I got puzzled wondering if it's the new research coming out he mentioned recently. It's described exactly the same way as this, the new obsession is clearly 'predictive coding'. But that's not what's notable. The hypothesis presented here is of the impact...
  12. rvallee

    Long-term course and factors influencing work ability and return to work in post-COVID patients 12 months after inpatient rehabilitation 2024 Müller+

    How the hell are we even supposed to counter an ideology that can't be bothered to make sense in adjacent sentences? This kind of nonsense would yield a fail in primary school. The authors need blame for this but a bunch of people read those sentences and thought nothing wrong of it. It's going...
  13. rvallee

    Long-term course and factors influencing work ability and return to work in post-COVID patients 12 months after inpatient rehabilitation 2024 Müller+

    So: They assume that rehabilitation works They don't know that it works They worked on rehabilitating some patients They can't say if it works, how, or whether it makes any difference, actually it seems to make no difference They have to justify the work they did, so they should develop #3...
  14. rvallee

    Alcohol Intolerance poll. Please do the poll even if your answer is no.

    I would say so myself. Slightly more pronounced on some aspects. Maybe more migrainy, if that makes sense. With some of the kind that comes with acute illness. I had COVID 2 months ago and there's some of that in there. Feels like being starved of oxygen, maybe being in a low oxygen environment...
  15. rvallee

    Comparison of [CBT] versus activity management, both delivered remotely, to treat paediatric [CFS/ME]: the UK FITNET-NHS RCT 2024 Metcalfe et al

    They still recommend CBT, emphasizing that it actually reinforces the evidence for it as first line treatment, while asking for more funding for more of the same research. This is how it will be presented, and this is how most interested parties will choose to interpret it. This is zombie...
  16. rvallee

    The Concept of ME/CFS, 2024, Edwards

    It would probably yield conflicting data since adaptation to the illness is so difficult to master. Lots of people push through things, may follow recommendations to avoid naps and so on, then later improve a bit by integrating naps, and now you have data points where less severity is associated...
  17. rvallee

    The Concept of ME/CFS, 2024, Edwards

    If only. I have only studied economics for a year, but I can assure you that serious health economics evaluations in chronic illness would yield very different recommendations than we see. Economics is a lot smarter than that. What we're seeing instead is pseudoeconomics applied to validate...
  18. rvallee

    Comparison of [CBT] versus activity management, both delivered remotely, to treat paediatric [CFS/ME]: the UK FITNET-NHS RCT 2024 Metcalfe et al

    The 'activity management' group is not a control. Let alone a proper control. What the hell does it control for? None of this is valid research.
  19. rvallee

    Review Trends and Hotspots in the Health Economics Evaluation of Chronic Fatigue Syndrome, 2024, Wan

    Makes a lot of sense from that perspective. TCM treatments can easily be shown to be just as 'effective' as any of the behavioral stuff. Using the same methodologies. They can also probably be found to be cheaper. It would actually be quite a coup, 'besting' Western medicine using its own tools...
  20. rvallee

    Incidence of post-acute COVID-19 symptoms across healthcare settings in seven countries, 2024, Xie+

    To get valid data out, first you have to enter valid data in. Until the problem of not entering valid data, and entering invalid data, is fixed, health care records are basically no better than Internet surveys. Barring a comprehensive study that does it all. There is indeed no code for PEM...
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