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This is very preliminary. To prove this: prospective studies with peri-menopausal women, started on HRT and monitor closely for dementia. That will take a decade, at least. HRT poses cancer risks.

From the discussion section: "Psychological symptoms are often involved in FM, as this and previous studies show, and pain treatment should include their management, with e.g., cognitive behavioural therapy intervention26. However, the findings about ANS function when comparing FM patients with...

Probably we are thwarting micro-organisms all day long, as that's what our immune system developed for. So cytokine levels may be meaningless. Just to add my n=1 re: primary FM. All my rule-out labs for immunologic disorders including lupus (I run a false positive ANA) have been normal. Sed...

This is not about LDN; I took a gummy bear of CBD/THC for the first time in years. I have never taken LDN. This is about attribution of improvement due to ingestion of a substance, a med for instance. I have FM for 27 years now, and not ME/CFS by Institute of Medicine diagnostic criteria (I...

Re: anectodal attributing an improvement to a new pill, etc. My story: I woke up this morning with a nearly refreshed sleep feeling and the increase of upper body muscle pain of FM over the past two days, rather excruciating, was gone. To what do I attribute this improvement? I had a big...

Eric Topol, of Scripps Institute, San Diego, and Professor of molecular medicine. Today's Washington Post, opinion piece. About the new variant, https://wapo.st/3w6Szg9

Comprehensive article from NYTimes on the new variant...

For perhaps a more balanced view on this paper by two experts, a virologist and an immunologist, Begins at about 31 minutes in. Vincent Rancaniello (hosts the blog that David Tuller writes in) is a professor of virology at Columbia. Here is the link to TWIV podcast Episode 972 with...

I started filling out the initial health conditions. I found the choices very old-fashioned and limited and therefore I lost interest in grinding out an hour of my time so that Younger can toy with machine learning.

Good idea to preamble the title of research article if it is a preprint, like: Preprint: Brazilian, etc. All MedRxiv articles are pre-prints. They haven't as yet been through peer review and are not the final, most accurate version.

Not having access to the full text, here is my take: Uh, how about cognitive dysfunction during a big flare-up? This study was done during only 8 consecutive days. PwFM can have a number of consecutive days without a flare-up of symptoms. But this doesn't reflect what happens frequently during...

Not every community has a pain medicine practice, but that's where I'd suggest chronic pain patients try to get a prescriber. Here's an earlier article about Ann Fuqua https://www.painnewsnetwork.org/stories/2020/12/2/help-us-end-the-suffering-of-chronic-pain-patients

Looks like the immunosuppressed (those lacking a spleen and alcoholics among the conditions listed) are at risk. Otherwise healthy people, not: https://en.wikipedia.org/wiki/Capnocytophaga_canimorsus My takeway message is: to be careful around dogs and cats, first aid to bites and scratches...

All bolding is mine. Small study. Initially 84 subjects randomized into three groups and at the end, only 41 participants remained. "...This study aims to compare the efficacy of three different exercise types on pain, health-related quality of life (HRQoL), depression, and body composition...

I've read elsewhere, with personal interest that knee replacement surgery on FM people, in a good number of cases, does not relieve pain in the knee (which would be expected) but does restore knee function. Any surgery is a risk for setting up another pain generating site in FM.

These professional, academic true believers (in exercise as a panacea) might have asked as few more FM patients: what happens to you when you try resistance bands or do bicep curls with two pound weights? Or even bend to the side. Never fails, no matter how many times I do it, to engender the...

Because I was socialized into the field of healthcare, I tend to give researchers more benefit of the doubt than they deserve. And, I cannot do a peer review; I don't have the knowledge. Yet, on Science4me, most of the FM research articles posted are psychology departments who have their...

I looked on Pubmed for any research using: salient network and fibromyalgia and zero results. I looked up salient network and found this entry on ScienceDirect. It is concerned with Parkinson's Disease (PD). From the textbook: Cognition in Parkinson's Disease James F. Cavanagh, ... Sarah Pirio...

Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers - Simona D’Agnelli, Lars Arendt-Nielsen, Maria C Gerra, Katia Zatorri, Lorenzo Boggiani, Marco Baciarello, Elena Bignami, 2019 (sagepub.com) This was one article in the references...

Yet another walking research report from Madrid, Spain. From a Department of Psychology and a hospital General Surgery and Digestive Disorders Unit (the latter hardly a field known for FM expertise). Since there is no drug regimen that helps more than 15% of FM patients decrease their pain 30...