Had my second Shingrix two days ago. A lot less of a problem than the first one. Did feel moderately shitty the day after, and I still have a bit of a sore arm. But nothing like what happened with the first dose.
The primary outcome measures will be based on self-reported physical health (SF-36 PPH) and treatment satisfaction (CGI-I).
At this stage continuing to insist on using unblinded self-report outcomes on their own is straight scientific fraud, IMHO.
Nah. They know exactly what they are doing...
The term post-exertional fatigue really needs to be stamped out hard. Those trying to get it into circulation and substitute it for PEM know exactly what they are doing and how misleading it is.
It is a part of their larger ongoing attempt to characterise it all as 'fatigue' (and its...
The NHS is institutionally buying into the narrative that increased numbers of heart attacks are caused by lack of exercise during lockdown, long covid is caused by anxiety and lack of exercise.
After the BPS club's behaviour over NICE, and now this, is there anybody still in any doubt about...
So both sets of data agree that a substantial fraction of patients have unexplained fatigue.
Which, presumably, includes being unexplained by the psycho-behavioural fear and deconditioning model so long promoted by the authors?
Suspiciously specific. Would seem to rule out a lot of...
However, we are still lacking a mechanistic understanding of the underlying psychophysiology.
Depends on who you ask. Some seem to think they have figured it all out, and it is now just a marketing problem.
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