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In the olden days they were worried about taking up too much space in the journal. These days that does not matter at all and researchers that don't provide basic data visualisations are simply inferior scientists...

All of the data was pooled into means, so we don't know. The SDs didn't really increase, so probably not in most participants, which is to be expected of healthy people.

Notably, of the ~8% increase in VO2Peak, most of it was in the first 4 weeks. The lack of a clear effect on mitochondrial or muscle fibre composition should not be too surprising. VO2Peak is rate-limited by the cardiovascular system - it is about how much oxygen can be delivered to the muscles...

From the ABC article mentioned above. Funny about that!

As I posted in another thread: R effective = Rz (reduction in transmission of breakthrough cases * proportion vaccinated + proportion unvaccinated)*(proportion vaccinated (1-Vaccine efficacy against symptoms) + proportion unvaccinated) Rz is the effective R for various social restrictions...

I don't think those figures are credible. They are not the result of test-negative case control studies like the Canadian and UK data. There are suggestions that those figures may be artifacts due to some errors and lack of matching exposure rates with suitable controls. At 6 months...

Viral loads at the start of an infection is not a sufficient proxy for transmissibility, given that those viral loads may diminish much faster since the immune system has already been primed, and hence be infectious for a shorter period of time. Only a community based (whole population) contact...

I hope that isn't true! Most of the models governments have been using have been based on (this is a random transmission model which works on the large scale, but not so accurate on the small scale): R effective = Rz (reduction in transmission of breakthrough cases * proportion vaccinated +...

This either suggests common pathology, or a lack of specificity of the SEID criteria, or poor operationalisation of the SEID criteria.

I think vaccinations against variants will be necessary in the future. It might not be annually, but biennially (every two years).

Mutations are a stochastic process, so more vaccinations means less mutations due to reduction in cases! Vaccines can apply 'selection pressures' that can lead to vaccine escape mutations, but the virus seems to be becoming more virulent just fine without the help of vaccines.

Is this corneal nerve fibre loss associated with neuropathic eye pain?

Some Cognitive Behavioural Therapy will fix that nerve fibre loss, no problems!

This is modelling of vaccination impact in Australia "Race to 80: our best shot at living with COVID" https://grattan.edu.au/report/race-to-80/ https://grattan.edu.au/wp-content/uploads/2021/07/Race-to-80-Grattan-technical-supplement.pdf The headline figure is that we can open up once we reach...

This is my experience also. It is fatigue in the sense that effort required for a given level of mental performance increases rapidly until no amount of effort works and the mental ability just disappears. It is most revealing when doing an exam - you start off with some ability, but by the...

They are trying to measure sensitised pain pathways, (what they're really trying to say is the brain is overreacting to pain signals). But study results tend to be equivocal or inconsistent between studies. There has been many attempts to state and or try and prove that all "functional somatic...

Or it means the effect is too small to be detected with the given sample size. But if you need 100 people to demonstrate a small effect, chances are the intervention is almost useless anyway.

Why innovate when you can just perform the same studies again and again on slightly different patient groups, despite never having any actionable results?

It will "shock" us? I guess that suggests they are still ill.

The most insulting thing about the whole Opoids crackdown is that prescription rates have declined, yet there is no effect on opioid related deaths in the USA. (prescription rates are /10000) I don't see a cause and effect relationship there. data from...