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Has some treatment suggestions: “Senotherapeutics are a new class of drugs and natural products that consist of two classes: senomorphics and senolytics [222]. Senolytics selectively clear senescent cells, while senomorphics are compounds that modulate their behaviour. If, as we argue here...

Diminishment of executive function aka cognitive impairment aka brain fog is one of the core features of ME/CFS. ADHD is also characterized by executive dysfunction. So I don’t think it’s really helpful for ME/CFS patients to also claim an ADHD diagnosis because it is already baked into the...

Also see this post Post in thread 'Very Wealthy people’s charities — News, Advocacy Ideas etc.' https://www.s4me.info/threads/very-wealthy-people’s-charities-—-news-advocacy-ideas-etc.39165/post-664944 Greg Brockman’s (likely billionaire from Open AI) wife has these plus autism minus ME/CFS...

If fatty B cells were responsible for the pathology of ME/CFS why didn’t B cell depletion with rituximab work as a treatment? The new cells that came back after rituximab were similarly “bad”?

“Had my immunologist appointment yesterday and honestly such a relief to talk with someone who sees Long COVID every day.We’re moving ahead with IVIG. They’ve got ~46 people on it and about 66% are responding.Really hoping I’m next and insurance covers. “

So immunoglobulin ranked about the same in both versions? This seems like the only potentially good treatment on the list.

“Today in @NatureMedicine we report that AI can predict 130 diseases from 1 night of sleepWe trained a foundation model (#SleepFM) on 585K hours of sleep recordings from 65K people—brain, heart, muscle & breathing signals combined. AI learns the language of sleep

Abstract Sleep is a fundamental biological process with broad implications for physical and mental health, yet its complex relationship with disease remains poorly understood. Polysomnography (PSG)—the gold standard for sleep analysis—captures rich physiological signals but is underutilized due...

Merged posts ------------ Patient-reported improvements from use of IMC-2 alone and IMC-2 and Paxlovid® in a Long COVID cohort: a case series William L. Pridgen, David Putrino Introduction: Long COVID (LC) is an infection-associated chronic condition and illness (IACCI) with no currently...

“I’m going to try and fund/build a team that will figure out treatment and medicine hypersensitivity in ME/CFS. Led by a man who I believe has big enough brains to pull it off. Discord server coming soon.”

“Ms. Bowman started taking BPC-157 and TB-500 last year hoping to address chronic fatigue, and said her sleep had improved right away. She logs her injections in the Peptide Tracker app, monitors her sleep and heart rate, and gets bloodwork done regularly.”

https://www.nytimes.com/2026/01/03/business/chinese-peptides-silicon-valley.html?unlocked_article_code=1.BlA.EnVI.FmgJ-R2kBu0h&smid=url-share Mentions chronic fatigue

“ Today is World Autism Awareness Day. My wife and I want to raise awareness of and help decrease any stigma around autism by sharing that my wife learned she has autism later in life—in her late 30s. It’s common for girls and women to have autism overlooked due to their often subtler signs...

How about this?— the sleep that you get from morning re-sleeping is less likely to be NREM sleep, so there is sleep but little or no clearance of junk (glymphatic clearance) which leads you to feel crappy—see here for example...

Yes, this is what I was referring to initially.

Posting because Eric Topol comes up frequently here. TLDR; nuts and salads https://wapo.st/4piAKUk

Interesting. I’m usually ok with daytime naps. It’s going back to sleep in the morning that kills me.

Here’s a Reddit thread from non ME/CFS people. “

Done

Good question! I don’t remember having anything like this when I was normal.