Search results

This seems to me cruel and unethical. Not only inflicting CBT on people with terminal cancer, but expecting them to fill in ridiculous catastrophising questionnaires.

I expect he gets rolled out at conferences to tell his story yet again. A sort of mascot for Sharpe and co. Or perhaps 'useful idiot'.

That description seems to imply it's simply a comparison of outcomes between their clinic and other available clinics. They don't specify what patient education and recommended management they use, saying it's individualised, so the results will be completely useless apart from providing...

Protocol: https://clinicaltrials.gov/study/NCT06025617 Study Start (Actual) 2019-06-01 Primary Completion (Estimated) 2025-12 Study Completion (Estimated) 2026-09 Enrollment (Actual) 290 Study Type Interventional Experimental: Intervention arm Patients referred by their GP under...

The sample size is miniscule. Each blob is for a named individual. I think it's just a way of illustrating where a few people responding to some sort of survey or belonging to an organisation live. It is interesting in the sense that it shows their respondents are mostly in Europe and North...

This is bizarre.

Won't they ever stop? Won't they ever learn?

This seems extremely judgemental. Have these questionnaires been properly validated on people with disabling chronic diseases? I'm guessing not.

Aren't we getting ahead of ourselves? I thought this was a phase 2 trial. We need to wait for the results of at least one full scale double blind controlled trial before we start talking about roll out. Remember how long it took for the series of trials of rituximab.

Since I can't see beyond the paywall, it's tempting to guess what they are talking about. My guess, clinician believes it's psychosomatic. Clinician tells patient a lie that they believe it's physical. Patient believes it's physical. Patient complies with treatment advice because they believe...

Thank you for continuing to engage with us on these thorny issues, and for your research work. We need more people like you. I find this situation really difficult to deal with. I accept that there are some symptomatic treatments some people find make a big difference for their quality of life...

The use of the word biopsychosocial 4 times in a short abstract is a big red flag.

I have tried yoga nidra and various relaxation visualisation audio over the years. I seem to be one of those contrary people who fight against someone telling me to relax. They were sometimes quite pleasant if I was already quite relaxed, but never when I'm stressed or insomniac. They just make...

I think it's an intervention only in the broad same sense as my adjusting my life and environment to avoid getting asthma attacks from things I'm allergic to, and to avoid things that trigger my migraine attacks. The GP's role might be to help me identify the triggers of these reactions if I ask...

I sleep badly quite often, particularly on the first night of an episode of PEM. I try to be relaxed about it, put on an audiobook I've heard before and enjoyed, and if it gets too bad or I get too restless, I put the light on and play a few rounds of something very boring and repetitive like...

This conference is on Saturday 20th September. It's available to watch online. From the website:

Getting back to the article this thread is about. I've just read it. The logic doesn't work, I think. The comparison cases they give of the triple drug treatment for HIV and the multipronged treatments for cancers are materially different, because in each of those cases by the time these multi...

This is the European Medicines Agency information on Xolair https://www.ema.europa.eu/en/medicines/human/EPAR/xolair#authorisation-details I don't see any mention of MCAS.

@darrellpf, can you clarify the source of these statements? Is this your own speculation, or do you have evidence you can point to?

This is an interesting discussion, and I think and important one in the context of suggested treatments such as the paper this thread is about suggests. I think it's fine for biomedical scientists and physicians to put their head together and come up with possible drug treatments that might be...