You're misrepresenting or misunderstanding the papers intentions. You've tried to make the paper about lipids and then questioned why they aren't mentioned in abstract. I think that's the confusion, you think we set out to prove lipids are part of the mechanism of me/CFS. That's not right. Maybe...
I previously saw that the MAGMA results in an anxiety GWAS showed the same top four enriched tissues as DecodeME:
This migraine study also matches for those top four tissues:
A multi-ancestry meta genome-wide association study of migraine among veterans: associations with traumatic brain injury, depression, and post-traumatic stress disorder
Abstract
Migraine is a neurovascular disorder that poses a high burden to Veterans, who face a greater risk than sex-matched...
That seems quite different from the MAGMA analysis on the decode results which found by far the brain to be most relevant.
——
On my migraine experience and overlap with ME/CFS. I just want to say that to me I experience migraine as a symptom of ME/CFS. I never got migraines before ME/CFS. And...
If it obesity or something specific that’s the concern (or just example) regarding ‘possibly explained by’ then would it be interesting to see whether pwme+obesity vs pwme-obesity is a big difference here. My brain can’t work out what we’d be equivalently ‘measuring for’ but I hope the gist...
If people with ME consistently develop a specific condition or range of conditions after the onset of their ME to a greater extent than the general population then it might be reasonable to expect there is some connection between their ME and that/those condition/s.
For example, though the...
My migraines are mostly of the "silent" variety (blind-spots, visual disturbance, scintillating scotoma, confusion, aphasia), sometimes there's significant pain, often not. There seems to be some connection between the migraines and ME/CFS (my collapse was precdeded by several months of...
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.