Except when they do —
Migraine and risk of stroke (2020, Journal of Neurology, Neurosurgery & Psychiatry)
Migraine and stroke (2017, Stroke and Vascular Neurology)
Migraine and Stroke: Perspectives for Stroke Physicians (2012, Stroke)
Migraine Headache and Ischemic Stroke Risk: An Updated...
It's important to understand that no one really knows whether someone getting worse sympyoms after the LP is due to physical harm or not but the absolutely crucial point is that irrespective of this if someone's baseline is seriously lowered as a result of the LP and they no longer have enough...
...it's just there is no actual irreversible harm to physical health being done (the same as how someone can have a really hideous painful migraine lasting days and then it goes and they don't have any actual brain damage. Migraines being something brain retraining is excellent at reducing or...
...some years ago at a point when my ME was deteriorating, with a predictable six hour delay drinking any caffeinated drink would trigger a migraine, though high sugar fizzy drinks without caffeine do not. Though more recently these now trigger IBS type symptoms.
I am assuming I developed an...
I believe the main study showing that severity and LC risk are correlated is one of the Al-Aly veteran's center studies. Several others since then have shown that there's no strong correlation. There might be others I'm not remembering right now. As it stands, it seems like severity of illness...
...expect less severe microthrombotic symptoms in patients taking OACs.
I am interested in this personally because I am having a long drawn out struggle with a migraine causing condition for which I am taking fibrinolytics bromelain and nattokinase because they do appear to reduce symptom...
...when we are much sicker and less able to function than usual. I think that needs a name and that name is PEM. It's sort of equivalent to a migraine or an asthma attack. It stops us doing what we can usually do.
Definitions of PEM by the US IOM and UK NICE both describe it in that episodic...
...just in PEM already - how it seems to have an impact that is hard to describe though shouldn't be as so many people have had or seen eg a migraine and how that would react to hostile sensory stimuli, except I guess it is the length of time of the impact issue that isn't got.
but I almost...
...levels and totally eliminated gluten from my diet, that I could say with certainty that consuming gluten triggered fatigue, malaise, migraine and IBS like symptoms after a twenty four hour delay, which would subside over several days, as long as I consumed no more gluten. Obviously with PEM...
Some subsequent papers elucidating the role of mast cells in IBS and migraine —
Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome (2025, Gut)
An interorgan neuroimmune circuit promotes visceral hypersensitivity (2025, Preprint: Research Square)
PACAP activates MRGPRX2 on...
PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain
Sbei, Sami; Moncrief, Taylor; Limjunyawong, Nathachit; Zeng, Yaping; Green, Dustin P.
Migraine ranks among the most prevalent disorders worldwide, leading to disability and decreased quality of life in patients...
...SNRIs) are effective for many, but the exact cause of depression is still debated (chemical imbalance, inflammation, neuroplasticity).
3. Migraine – Triptans and CGRP inhibitors provide relief, but the fundamental cause of migraines (vascular vs. neurological) is still unclear.
4. Epilepsy...
I think the basic proposal is that this is evidence of neuroinflammation / leaky blood-brain barrier. That the water molecules in the perivascular space are now restricted in Brownian motion. Normally it might be expected to have content mostly like CSF as the current thinking is that CSF...
...due to its mortality and global panic—and later due to long COVID challenges. One of these long COVID symptoms, headache, often resembles migraine-like features. Migraine shares similarities with COVID-19 and long COVID, yet the influence of sex is understudied. Our primary objective was to...
...of time it can be done for (egg-timer draining faster) and takes more out of you.
If you consider someone well just having the flu and a migraine then it isn't just about feeling rotten but the brain having to battle that at the same time as whatever task. Plenty of people who have come into...
It's not as bad as some of the drivel we have seen from BACME, with its recognition of ME/CFS as a long-term illness and acknowledgement of severe ME/CFS. But yes, still not evidence based.
Authors:
Anna Gregorowski
Chair and Consultant Nurse
British Association of Clinicians in ME/CFS (BACME)...
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