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They can still argue that it is something about a patient's thoughts and/or the behaviour that flows from that faulty thinking that is causing both the symptoms and the differences in brain structure that they believe they have found. I think it was found that London taxi drivers have a...

From the article: I know it's not good to make comments on a brief excerpt of what someone said, but I think that reported testimony sums up a lot of what is wrong with doctors' approach to ME/CFS. First, thinking that specialist knowledge of ME/CFS was needed to make a difference. As...

So many options for correlations, and even then, there wasn't that much of note. I'm pretty sure that if you applied normal distribution probabilities for 134 features to 180 individuals randomly put into 3 groups, most of the time you would find some combination of some features that separated...

Not to mention the nearly 100 posts on this thread, many about the links drawn between the fanciful EEfRT finding and various other things: Grip test results and brain imaging in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

:laugh:, at least all the right letters are there.

A discussion on this topic has been moved to Personality as a risk factor for ME/CFS and similar diseases

That sounds encouraging Midnattsol. Members may be interested in this thread about Grete: Clinical psychologist Grete Lilledalen about ME and CBT/GET.

That's bizarre. Yes, sadly, I don't think these papers are worth much.

Table 2: Only around 15% of the PASC people reported fatigue and lack of energy as a reason for attending the clinic. Around 20% of the PASC people reported dyspnea and respiratory issues as a reason for attending the clinic. Quite a lot of co-morbidities too. CpGs = groups of consecutive...

A Lancet paper - New York authors The authors don't seem to be understanding that PASC is a collection of different things. It's not looking good for a homogenous sample. Nope.

I don't know of course, but this study seems really underpowered, given the numbers, especially of the post-Covid-19 controls, and the variable percentages of males in the groups. I would have thought that epigenetics would have a huge amount of noise, with sex right up there as a source of...

It looks to me as though the athletes were back to training very quickly. The mean length of the Covid-19 symptoms was just 3 days. It was interesting to read this, about another study, in the light of claimed incidence rates of Long Covid: There is the question of whether reduced fitness...

Chinese study First, just a note about the ethics. It sounds as though the athletes may have been deliberately infected for this study. The authors say the study got ethics approval and the participants were informed. But these are 17 year olds young, who are in a residential facility and...

Thanks SNT. Looks like a handy tool. For those like me not up with the jargon: I don't think post-exertional malaise is a MeSH term? (excuse the next snide comment) You would think with access to all that literature that the authors would not have written those two phrases so definitively...

We have merged the news of the Times article into this thread about the Marshall Gradisnik NCNED study. The thread about the genetic study is here: Evaluation of a Gene–Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness..., 2022, Haley et al

This is an interesting paper, and it's clearly written. Inevitably, there are many assumptions that are arguable. The author notes that the analysis does not include costs associated with carers, which would, I think make a difference. And it's not just the carer of the person with ME/CFS...

Rehabilitation clearly comes with a substantial cost to the participants (which include parents in the case of paediatric patients) and to the health system. There's a couple of problems there. While it was valid to survey people who didn't start a hospital-based rehabilitation programme to...

[Myalgic encephalomyelitis : etiopathogenesis, diagnosis and treatment], 2024, Scherrer et al in French, paywall, authors are Swiss