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I was wondering what is normal for any Norwegian population, particularly in relation to how far north they live and depending on the time of year, particularly with vitamin D.

I have not looked at the paper itself, but one might expect time post onset and severity to also link to taking supplements. Over the course of my ME, my maximum level of taking supplements was between two and four years into the condition, when I was trying everything and anything, but once I...

Thank you for all the work that went into this process.

I don’t know any details of the trial, if it is a trial, but a couple of people I know in high risk groups for complications from Covid here in the UK were contacted in December requesting if they test positive for Covid to immediately make contact to receive a (new?) drug treatment hopefully...

29 years post onset initial glandular fever (confirmed active EBV infection), symptoms continued unchanged, on to ME/CFS diagnosis some six months later (GP preferred term CFS because he regarded that as etiologically neutral, though different GPs, Consultants and Researchers have used...

There seems to be a fundamental gap in the theoretical underpinnings of much rehabilitation, it takes the idea that if you have a broken leg you stimulate muscle recovery and return to normal activity by physical activity and generalises it to other unrelated conditions, without asking why. For...

What don’t yet know is if Long Covid results in an assortment of cooccurring problems including ME/CFS, that is the original virus triggers conditions/symptoms only indirectly related to each other such as specific neurological damage or lung damage, which for some also includes the condition...

You do make the important point @Snowdrop that research so poorly designed that it is never going to produce any meaningfully interpretable results can never be cost effective in terms of science or medicine, despite many researchers and clinicians building their careers on the back of it. What...

Thank you for the link. I saw ‘pre print’ and just assumed the full article was not yet published. This is what they say in terms of aetiology: This is what they say about patient selection: So those those in the functional somatic syndrome group had a number of distinct disorders lumped...

Do we know if cortisol levels relate differentially to physical stress and psychological stress? A health condition, regardless of its aetiology, may be a source of psychological stress but it may also be a cause of physical or biological stress.

I am not sure I understand the difference between their two ‘functional’ groups: As the article is not yet available we don’t yet know any more about how people were allocated to each group, whether this was based on questionnaires or clinical judgement. Given there is no positive evidence...

Considered the therapy of first choice by whom?

Suggestions for change in the final version could come from the Lancet editorial team, from peer reviewers or be made by the authors themselves.

I don’t think all the others were from New York, so unlikely that they would all have had a booster on the same day or the same place as my niece. Where there is high levels of the virus, even if people take lateral flow tests, there is going to be a number of people getting the booster who...

Interestingly, after my Moderna booster I had a very bad couple of days with lots of aches and pains and some lung issues, which resolved fairly quickly. However I have slept a lot more than usual in the following two weeks, which has mostly been a positive as I have largely been sleeping...

Here in the UK I am aware of several individuals classified in the highest at risk grouping as having been offered a fourth injection, though it seems as something coming soon rather than something to book for next week. The two I know best (one with a lung condition and the other with type 1...

Is it in any way possible in this context to distinguish between ‘pain catastrophizing’ and accurate insight into your body’s pain responses?

My IBS has resolved over the years into a clear predictable pattern: episodes are triggered by specific foodstuffs, either high sugar content or foods that I am specifically intolerant to, being a day or so into an episode of PEM or in the later stages of a migraine where the pain is severe...

There must be a margin of error. My niece in New York recently tested positive for Covid two days after having the booster. She was having lateral flow tests every few days, and met with some friends (all twice vaccinated/tested negative) over the weekend before last, then two days later she...

Isn’t describing this as a ‘pioneering treatment’ rather than an ‘experimental intervention’ rather prejudging the issue? Someone had what they thought was a good idea and then rather than evaluating it experimentally set out to make money from it.