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This was a while ago, but what do you mean by reactivation of immune responses? That the immune system has become more sensitive or that it overreacts to normal things? I believe I remember reading something about how the innate immune system halts the energy production in cells for the first...

Says this: With the largest machine, you can run ~5,000 sequences a year. I assume the prep can be done while you run another batch, so it doesn’t add time to the processing duration. I have no idea which machines they use and how many. Source

This seems to be pretty niche and technical, so most people are probably not able to discuss it, including myself. The authors of the paper you posted have substantial financial interests in MAO-B, so they will probably push for studies and trials if it’s worthwhile.

Giovanni Marasco: supervised, designed the study, collected and interpreted data, and drafted the manuscript. Keren Hod: designed the study, collected and interpreted data, performed statistical analysis, and drafted the manuscript. Giovanni Barbara: supervised, critically revised and approved...

I still think it’s beneficial to be able to explain to regular people that the gift is in fact a turd, and why that is.

Why is the BPS model true? - Because Engel wrote it down. How did he know it was true? Did he prove it? - No, he just knew somehow. It’s funnier when you know that ‘engel’ means ‘angel’ in Norwegian.

Similar patterns have likely been found for ME/CFS in Norway: https://www.s4me.info/threads/socioeconomic-determinants-of-me-cfs-in-norway-a-registry-study-hilland-and-anthun-2023.33011/

Someone must have had fun making the graphical abstract. Less is apparently not more.

68 authors!

Maybe a bit of both. My parents don’t fully understand either, even though they have to care for me because I’m bedbound as a result of covid. It’s difficult to question your reality, but it’s also convenient for politicians to just not do it properly.

@Peter Trewhitt @MittEremltage That’s the level of the Norwegian discussion as well. Some politicians have been talking about LC, but they don’t seem to understand the gravity of the situation.

I don’t expect you to be able to follow everything, you’re already on top of so much! We have a huge debate in Norway regarding the increase in sick leave, and fortunately some researchers and doctors have been trying to explain that you have to consider covid as a massive contributor. It’s a...

@Midnattsol good points!

I hope the Covid Association is trying to tell them that the increase probably is an increase in LC?

Average time to diagnosis to Norway was somost 8 years in one pre-covid survey from the Norwegian ME/CFS. Many report an instant onset from e.g. an infection, so it seems like this is less likely (although it can’t be excluded).

Thank goodness these people could help the alternative providers with writing a business case.

A normal CPET is done like this: Procedure Attach electrocardiogram (ECG) electrodes and blood pressure cuff. If using a bicycle ergometer, adjust seat to proper height level and null bike. Obtain baseline ECG, blood pressure, and VO2/VCO2 measurements. Begin exercise period and record data...

I understand that they are only using an average, but that’s about the only thing I understand!

If thoughts can affect any part of the body in any way, then I should be able to make myself turn green without any external interventions. If you tell me that’s impossible, I challenge you to define what is possible and not. You should quickly come to the realisation that there are physical...

The speculate about of few mechanisms, but they go way beyond the evidence.