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  1. Mij

    Depressive inclinations mediate the association between personality (neuroticism/conscientiousness) and TikTok Use Disorder tendencies, 2024

    Abstract Background We introduce a novel measure for assessing TikTok overuse, called the TikTok Use Disorder-Questionnaire (TTUD-Q). As part of ongoing investigations into the suitability of the World Health Organization’s (WHO) framework for diagnosing Gaming Disorder in the context of social...
  2. Mij

    'Curable' mind-brain training app and ME/CFS, including the role of Fiona Symington

    The healing ME link where she talks about coming at this from a "Christian perspective . . ." Beliefs . . .
  3. Mij

    'Curable' mind-brain training app and ME/CFS, including the role of Fiona Symington

    Written a few hrs ago: "Never in my wildest dreams did I think I'd be told I didn't have M.E - this was my community for 14 years and I'd only experienced kindness from them. It is disgraceful to invalidate others experiences".
  4. Mij

    San Francisco Chronicle: Fear of COVID fades even as virus remains a ‘significant threat,’ survey reveals

    The Pandemic That Never Left- Heart FAILURE. Although the mortality related to COVID-19 has eased significantly from 2021 highs, COVID-19-related mortality was LOWER than Heart Failure-related mortality both at its peak and throughout the pandemic.
  5. Mij

    Open (Boston, Massachusetts) Characterizing Non-Restorative Sleep in Post-Viral Disease to Advance Intervention Innovations (ME/CFS, LC, Healthies)

    If they can get to the root cause of why some pwME experience severe insomnia that would be a great relief for many. I had a close friend who suffered severe insomnia from day one of post-infectious illness for 18 years. I don't experience insomnia and getting refreshed sleep will not...
  6. Mij

    Covid-19 vaccines and vaccinations

    Sars-CoV-2 vaccine-elicited immunity after B cell depletion in Multiple Sclerosis. "Noravax homologous boosting induced a significantly more robust serological response than mRNA boosting"...
  7. Mij

    Clinical characterization of new-onset chronic musculoskeletal pain in Long COVID: a cross-sectional study, 2024, Omar Khoja et al

    Abstract Purpose: New-onset chronic musculoskeletal (MSK) pain is one of the common persistent symptoms in Long COVID (LC). This study investigated its clinical characteristics, underlying mechanisms, and impact on function, psychological health, and quality of life. Patients and methods: 30...
  8. Mij

    Protocol Evaluating the Efficacy of Remdesivir for Long COVID Following a Confirmed COVID-19 Infection. (ERASE-LC), 2023, Mark Faghy, University of Derby, UK

    Exclusion Criteria Recognized as a 'severe risk' of experiencing post-exertional malaise following engagement in physical tasks. Determined using the De Paul symptom questionnaire Why would PEM be listed as an exclusion for this trial? https://classic.clinicaltrials.gov/ct2/show/NCT05911906
  9. Mij

    Spectrum of COVID-19: From Asymptomatic Organ Damage to Long COVID Syndrome

    Abstract Long COVID, as currently defined by the World Health Organization (WHO) and other authorities, is a symptomatic condition that has been shown to affect an estimated 10-30% of non-hospitalized patients after one infection. However, COVID-19 can also cause organ damage in individuals...
  10. Mij

    Australia: News from Griffith University, National Centre for Neuroimmunology and Emerging Diseases (NCNED)

    It's really starting to feel like M.E is an afterthought disease.
  11. Mij

    Early tx with fluvoxamine, bromhexine, cyproheptadine and niclosamide to prevent clinical deterioration in pts with Covid-19. . .clinical trial, 2024

    Tread on our RCT published in Lancet’s where we show early treatment with 2-drug combos of fluvoxamine, bromhexine, cyproheptadine, niclosamide in COVID ✔ completely prevented deterioration viral load inflammatory cytokines Long Covid risk
  12. Mij

    Early tx with fluvoxamine, bromhexine, cyproheptadine and niclosamide to prevent clinical deterioration in pts with Covid-19. . .clinical trial, 2024

    Full Title: Early treatment with fluvoxamine, bromhexine, cyproheptadine and niclosamide to prevent clinical deterioration in patients with symptomatic Covid-19: a randomized clinical trial, 2024, Dhammike Leshan Wannigama et al Summary Background Repurposed drugs with host-directed antiviral...
  13. Mij

    Covid-19 vaccines and vaccinations

    Persistent immune imprinting occurs after vaccination with the COVID-19 XBB1.5 mRNA booster in humans M. Alejandra Tortoricic; Amin Addetia; Albert J Seo; Jack Brown; Kaiti Sprouse; Jenni Logue; Erica Clark; Nicholas Franko; Helen Chu; David Veesler Highlights XBB.1.5 COVID-19 mRNA vaccine...
  14. Mij

    USA: The RECOVER Initiative - Long Covid research

    https://trials.recovercovid.org/autonomic NIH opens long Covid trials to evaluate treatments for autonomic nervous system dysfunction Part of NIH’s RECOVER Initiative, trials will test at least three treatments for symptoms such as fast heart rate, dizziness and fatigue...
  15. Mij

    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells, 2024, Wei Bu et al

    https://www.genengnews.com/topics/infectious-diseases/epstein-barr-virus-has-vulnerable-sites-exposed/
  16. Mij

    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells, 2024, Wei Bu et al

    Highlights• Isolated mAbs to EBV gp42, which is required for the fusion of the virus to B cells gp42 mAbs A10 and 4C12 use different mechanisms to inhibit EBV fusion to B cells Two distinct sites were identified on gp42 for receptor binding and for fusion to B cells gp42 mAb A10 prevented...
  17. Mij

    Do people with ME/CFS and joint hypermobility represent a disease subgroup? An analysis using registry data, 2024, Kathleen Mudie et al

    Merged thread Do people with ME/CFS and joint hypermobility represent a disease subgroup? An analysis using registry data, 2024, Kathleen Mudie et al Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic, multifaceted disease that affects millions globally...
  18. Mij

    Long-Term Effect of Randomization to Calcium and Vitamin D Supplementation on Health in Older Women, 2024, Cynthia A. Thomson, PhD, RD et al

    Abstract Background: Although calcium and vitamin D (CaD) supplementation may affect chronic disease in older women, evidence of long-term effects on health outcomes is limited. Objective: To evaluate long-term health outcomes among postmenopausal women in the Women’s Health Initiative CaD...
  19. Mij

    Association between loss of hypercoagulable phenotype, clinical features and complement pathway consumption in COVID-19, 2024, Daisuke Kasugai et al

    Background: Coronavirus disease 2019 (COVID-19) features a hypercoagulable state, but therapeutic anticoagulation effectiveness varies with disease severity. We aimed to evaluate the dynamics of the coagulation profile and its association with COVID-19 severity, outcomes, and biomarker...
  20. Mij

    Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19, 2024, Hanson et al

    My daily dose of iron supplementation was 27mg w vitamin C. It took 9 months to bring my ferritin up to 55 from 5 and it would drop back down to 14 within 2 months after I stopped taking iron. Alternate-day administration of 100 and 200 mg taken from the link posted above would make sense...
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