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This suggests a strange possibility to me. What if some of the inconsistency in past patient cytokine levels has been caused by differing amounts of effort patients have had to expend to get to their doctor's office to have their blood drawn?

When Vanessa Li passed away, the team at Columbia's Center for Infection and Immunity (Lipkin, Hornig, et al.) said that they were dedicating their 2015 cytokine paper to her. She had led the patient fund raising campaign for them.

"Hmmm. Disappointing. Well, let's move on to you, Captain Piett. Have you found these online sessions helpful?"

Although I had a recurrent sore throat when I first became ill - in fact, my onset seemed to have been precipitated by a really severe sore throat (that may have been strep) - sore throats didn't really bother me much after the first few years of ME. When I heard about crimson crescents, I...

Of course, psychological stress is not the only kind of "stress" there is. What if you get into some kind of stable "loop" or altered homeostasis due to the physical stress of a severe infection ("worst flu ever")? Or the physical stress of a bodily injury? What if your body's response to...

No, you are right. As far as I know, the GWI phase one trial began in Dec 2017. She says that, if the results of that trial are promising, then she hopes to be doing a ME/CFS trial in early 2018. I was just saying that a trial said to begin in "early 2018" could start as late as March/April 2018.

This is what Dr. Klimas says in the video above, which was recorded in mid-October 2017. Early 2018 could be as late as the March/April time frame. From the above, it seems like the gating issue for pursuing an ME/CFS trial at this point would be whether or not the Gulf War phase one study was...

From earlier in this video, in her conversation with Dr. Nahle, I got the impression that, in the event that the Gulf War Illness trial showed good results, they would proceed with an ME/CFS trial relying entirely on computer simulations - as opposed to going through the lengthy process of...

In the video, she is actually talking about a two step protocol that, hypothetically, could treat Gulf War Illness. I would assume that their protocol for ME/CFS would be different in some way, i.e. other drugs, or different number of steps, timing, etc... The only drug she mentions in the...

This sounds somewhat similar in concept to what Nancy Klimas has been talking about, i.e. flipping homeostasis back to normal in Gulf War Illness (and also in ME/CFS). The treatment she is working on for GWI is a two step procedure where they first administer a drug to "block the...

I read about this. I believe they inject a really, really small amount of the two agents into a solid mass tumor. Somehow, this stimulates the immune system to go after the particular type of cancer cell that is the targeted by the injection. So much so that the immune system goes after the same...

This sounds like it might be along the same lines as Nancy Klimas' work on altered homeostasis.

Leonard Jason's 1999 prevalence rate was 422 CFS cases (Fukuda) per 100,000 adults (0.422%), with a 95% confidence interval of between 285 cases and 559 cases per 100,000. Using a current US adult population estimate of about 251.5 million (census data here) you'd get an estimated 1,061,300 US...

Oh, dear. Does this mean that this trial is going to be another one of those "beautiful ocean liner" things? This time with the good ship "SMILE" ?

Re-quoting part of Dr. Ramsay's article above... It looks like this 1979 paper was the result of that investigation: Odd about the enzyme pattern resemblance to DMD. I don't think I've ever heard that before.

I'm not sure that I've seen this linked elsewhere, but the entire November 1978 issue of the Post Graduate Medical Journal was devoted to ME and is online. It includes articles by Melvin Ramsay and J. Gordon Parish among others. I thought it might be of historical interest to some. Here, ME is...

"Subjugation"? "Paternalism"? "Loss of self determination"? "Enslavement"?

Dr. Montoya concludes by saying this: Amen.

Are you referring to the 100% identity of the ME/CFS gene expression signature with that of Systemic Inflammatory Response Syndrome referenced at about 14:10? Until recently (2016), the SIRS criteria were being used to diagnose probable sepsis.

I'm putting all of my money into tulips.