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Doesn't this imply that these symptoms are due to hypoglycemia, not ME? How do you sort the two out? Do dietary changes that help hypoglycemia help you, or was it only the medication that helped? When I was initially getting sick , I thought I was having hypoglycemia too. My blood sugar...

Isn't it more likely that insulin resistance is a downstream effect of ME/CFS rather than the other way around? Blood sugar regulation problems can be caused by dysautonomia, can they not?

What are these other processes?

The authors don't seem to have a clear understanding of what long COVID is. However, given that all of the people who were still symptomatic after COVID had a different methylation pattern, doesn't that show something of interest? Also, from figure 4 above- are they making hay of that result...

What effect does lactoferrin have on the iron deficient? I feel better when I take iron.

I would love to be able to live without crashing, but at this point personal hygiene flattens me, so I just can't.

I've always thought non celiac gluten sensitivity was a nocebo effect or misdiagnosed IBS.

Yes, I think it very much comes down to what healthy people think we deserve. For example, I have heard things like disability payments and disability accommodations being referred to as secondary gain. It's a shocking misunderstanding of how disability and accommodations are meant to work...

There's a researcher I like at University of Colorado, Daniel Goldberg, who looks at disability stigma and disability payments/accommodations. Looking at the history of railway spine, he clearly connects it to money. People claiming to be hurt in railway accidents were entitled to payment by...

Of course MS is a psychosomatic disease. [sarcasm] There's a new paper out on it. "It includes the first mapping of maladaptive beliefs and behaviors arising from developmental challenges that are common to people with MS. An initial comparison shows these may be distinct from those of people...

I find listening to Alexander teachers on youtube helps my insomnia. This sort of thing puts me to sleep.

What beautiful irony this is! You really need to publish somewhere.

And they are still beating the dead horse of "unexplained symptoms".

If thinking harder worked none of us would have had to leave work or school.

Jason Leonard has a critique of the study too. https://www.medpagetoday.com/opinion/second-opinions/109274?xid=nl_secondopinion_2024-03-24&eun=g2174355d0r

That is my sense as well when I hear depressed people describe their symptoms and experience. I was wondering what biology he was referring to, but didn't want to waste energy listening to him if he was talking nonsense. In my reading about ME/CFS I haven't come across any biology that is...

So I had started watching a youtube video on depression by a professor at Stanford. It was sounding really good until he mentioned something called atypical depression (which I had not heard of before) and how it was biologically similar to CFS. At that point I got upset and stopped watching...

Well, I did just read the abstract and not the whole paper. I may have leapt to some conclusions!

How can people keep claiming this?! Sure, we don't know everything (or even enough), but this constant refrain of can't find the patho despite decades of research is a back handed way of hinting that there is no patho, because you know, it's all in our heads. Why can't they just say it's...

Yes, this really hits the nail on the head. I didn't read the article, but I can imagine it based on this comment. What gets me about these type of articles, and lifestyle medicine in general, is how patient blaming it is. If only you would change your behavior, the illness would change or...