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Oh, we need new paradigms. There's no good models to explain PEM. But for goodness sake, not this. It's far from new anyways.

Paxlovid rebound only occurs in 10-30% of people, and when it does, it's rarely serious. It seems to me like there's nothing to lose. If you get rebound your illness will probably be less severe than it would have been, since your adaptive immune system has more time to respond.

There are good ways and bad ways to link together mental and physical healthcare and this sounds like a bad way. Discussing the effect of anxiety and depression on long-term health outcomes and such.

Media coverage in the Conversation: Long COVID stemmed from mild cases of COVID-19 in most people, according to a new multicountry study https://theconversation.com/long-covid-stemmed-from-mild-cases-of-covid-19-in-most-people-according-to-a-new-multicountry-study-195707

Inflation is hurting me less than most people, since US disability benefits are tied to inflation, and wages are falling behind. However, that ignores the fact that I'm living on around 40% of the median salary in my country.

17.6% had long-term symptoms but only 6.6% at 24 weeks, which means most children who get long Covid recover.

That's a fairly middling description of ME. They vaguely reference PEM as "exhaustion", describe cognitive impairment as a psychiatric symptom, then describe depression as an ME symptom. (It's not.) I'll cut them slack because PEM-induced mood swings are real, but it's odd of them to emphasize that.

Oh, I even forgot to add that one. Edited.

They're STILL not asking about PEM.

They finally corrected it by editing the title. Now it says: 25 per cent of COVID patients become ‘long haulers’ after 12 months: Mac study Which is broadly in line with other studies.

So we're just gonna give up. Nice job.

Can we just give people with intractable chronic pain as much drugs as they want? They're in pain for heaven's sake. (That's slightly hyperbolic.) I see multiple arguments in favor of liberalizing the rules around painkillers: Doctors/policymakers are demonstrating a basic failure to apply the...

I'm in favor of that. Cognitive impairment/dysfunction or examples of things you're unable to do will be taken more seriously.

The biggest problem I have with this study is that there's no conceivable way it will make people's lives better. It could well worsen systemic ableism by fobbing off autistic people's signs of serious illness as psychosomatic. People with more signs of autism are more likely to report having...

I have both PTSD and ME. They're not even vaguely the same. And neurasthenia likely included many people we'd diagnose with ME, dysautonomia, or fibromyalgia today.

It's gonna be a small double-blind RCT at 42 participants. So fairly small. Hopefully a larger study will be conducted if it shows promise.

This seems like concrete and significant progress!

That's why I strongly oppose use of the term CFS. And I agree that consumption of alcohol is strongly negatively correlated with ME. An old survey-type study seems to indicate that most people with ME/CFS drink little to none.

Sigh. Some people were banking on China taking LC seriously. That seems unlikely at least for now.

Ever the optimist, I find things to be hopeful for: DecodeME! Results from NIH RECOVER's treatment trials Progress on the long Covid drug pipeline in general (BC-007, CT-38, gaunfacine, etc.) The OMF's treatment trials (presumably preliminary) I'm expecting strong results from Decode. 20k...