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  1. Ravn

    Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in ME/CFS - 2020 - Schreiner

    Thinking out loud. On the one hand we have findings showing ME mitos outside the serum act more or less the same as HC when unstressed but can't keep up when extra demand or stress is placed on them. So problems independent of serum. On the other hand we have various serum swap studies that...
  2. Ravn

    Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in ME/CFS - 2020 - Schreiner

    Phew! That was one epic read. Maybe Prusty could only get this published as a single paper but it would have made more sense to split it into at least two, and probably more, separate papers. That would also have made it easier to write more informative abstracts. It would definitely have made...
  3. Ravn

    Mini-crashes in late afternoon / early evening?

    Not sure if my experience is the same 'slump' you others are describing but I do get a daily period of feeling decidedly off. Lasts about 2 hours. Builds up gradually over half an hour or so, stays high for the next hour and gradually subsides again until I'm back to "normal". It's not related...
  4. Ravn

    Advice from 'experts' on post-viral fatigue following Covid-19 (NHS Oxford Health, Science Media Centre, ...)

    What a relief! That leaflet made our progress feel like one step forwards and twenty steps back. Thanks so much to everyone who worked towards getting rid of it.
  5. Ravn

    Coronavirus - worldwide spread and control

    Don't think this paper has been posted? One for those who like looking at graphs and statistics. Iceland has tested a high proportion of their population, including random testing, and here they're presenting the resulting data. There are the usual numbers tested vs numbers tested positive...
  6. Ravn

    Coronavirus - worldwide spread and control

    We sure are hoping and crossing every finger and toe and any other crossable bodypart! As @Rosie said today we were down to 5 new cases. Though that could well go up again in the next few days as another repatriation flight has just arrived but at least any infected persons on there will be...
  7. Ravn

    Coronavirus - worldwide spread and control

    NZ's daily new case totals include confirmed and probable* cases. Today, for example, we had a total of 9 new cases, made up of 7 confirmed (by test) and 2 probable cases. Do all countries do this, or do some only count confirmed cases - which would make comparisons (even more) misleading...
  8. Ravn

    Coronavirus - worldwide spread and control

    I wonder if we aren't talking slightly past each other here? It's worth noting that when it comes to viruses there's a difference between eradication and elimination. Eradication refers to the virus being gone - completely and everywhere - it doesn't exist anymore. Eradication is extremely...
  9. Ravn

    Coronavirus - worldwide spread and control

    Arrgh! The resistance to NZ's elimination strategy is getting organised. I can't find any reason for it other than that they're a bunch of academics peeved that the government has chosen to listen to more cautious voices, rather than to them. I do wonder though if they don't also have other...
  10. Ravn

    News from Aotearoa/New Zealand and the Pacific Islands

    For information: The article links to 3 information sheets about PEM and Pacing we've discussed and fine-tuned in this members-only thread: https://www.s4me.info/threads/feedback-please-draft-info-sheets-pem-pacing.13712/ The direct links to the information sheets are...
  11. Ravn

    News from Aotearoa/New Zealand and the Pacific Islands

    Just out of interest, does anyone have access to the e-learning assessment on this article? If I understand this correctly, doctors can read the article and then do some sort of assessment to claim some sort of continuing education credits?
  12. Ravn

    News from Aotearoa/New Zealand and the Pacific Islands

    I particularly liked this bit: Pacing before final diagnosis is rarely suggested but so important. If at the end of the diagnostic process it turns out the person didn't have ME after all - no harm done. They may be marginally less fit than they might otherwise have been but nothing that can't...
  13. Ravn

    News from Aotearoa/New Zealand and the Pacific Islands

    I don't know the system so don't know what to say about timing. Are the people who usually deal with Health Pathways currently flat out with Covid-19 response planning? In which case timing would be bad. Or are they like EDs and GPs and twiddling their thumbs right now? In which case timing...
  14. Ravn

    News from Aotearoa/New Zealand and the Pacific Islands

    :thumbup::thumbup::thumbup: Apparently many GPs aren't very busy right now, with many people avoiding going to the doctor unless it's absolutely necessary. Here's hoping some GPs are using that downtime to do some upskilling with this article. Given the current knowledge many GPs have - or...
  15. Ravn

    News from Aotearoa/New Zealand and the Pacific Islands

    I've been approved. Took maybe 5 days, so 2-3 business days. Don't think age is a factor as I'm much too young for the Supergold card. Unfortunately approval doesn't translate into actual delivery slots in my rural area which is serviced by rural delivery courier. Maybe it's a bit better in...
  16. Ravn

    Why the concerns that antibody immunity to coronavirus will only be short-lived?

    No references, sorry, just a vague recollection of reading that those estimates are based on other corona virusses which, apparently, typically only induce short- to medium-term immunity.
  17. Ravn

    Coronavirus - worldwide spread and control

    Further on lockdown effectiveness, unsurprisingly Google is keeping track of it. You can download a pdf country report which gives whole country figures as well as regional breakdowns of how much people frequent certain places (work, shops, parks, home, etc) before and after lockdowns. Though...
  18. Ravn

    Coronavirus - worldwide spread and control

    This article compares the timing and strictness of lockdowns in a number of countries we don't hear much about, like Estonia and Paraguay, and how they're faring. So far the evidence points towards locking down early and hard as the least bad approach...
  19. Ravn

    Coronavirus - worldwide spread and control

    Editorial in the NZ Medical Journal outlining how NZ's response to covid-19 started with dusting off the pandemic influenza plan - essentially a mitigation strategy since nobody believes influenza can be eliminated - before turning comparatively quickly to an elimination strategy when it became...
  20. Ravn

    If there was a study to follow ex-COVID-19 patients what would we want to see recorded?

    @Andy Are you in contact with Mike Snyder? He would be an obvious candidate to set up something involving wearables to track both covid-19 infection and recovery - or descent into ME - as discussed in several posts above.
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