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  1. Snow Leopard

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    People like SW often retweet things they haven't actually read...
  2. Snow Leopard

    Trial By Error: Re-visiting My Questions for PACE Professors

    I'm not anywhere near as optimistic as that. Nothing is going to change until we have some understanding of the pathology.
  3. Snow Leopard

    Cochrane Database Syst Review - Psychosocial interventions for conversion and dissociative disorders in adults (2020) Ganslv et al.

    Wait, I got it: Magic! Someone must have cast a hex on them! No wait that's not it how about: They displeased the gods! Perhaps they were nasty people in a past life and have to atone in this one?
  4. Snow Leopard

    High-fidelity discrete modeling of the HPA axis: a study of regulatory plasticity in biology (2018) Sedghamiz et al.

    Note how all of the references for "enhanced sympathetic activity" are papers written by Wyller! He takes self-citation to a whole new level. Studies of adults have not found differences in levels of catecholamines compared to healthy controls. The concept of "sustained arousal" also...
  5. Snow Leopard

    High-fidelity discrete modeling of the HPA axis: a study of regulatory plasticity in biology (2018) Sedghamiz et al.

    I don't get too excited about results that largely overlap with healthy sedentary individuals like most of the cortisol studies I have seen. If it was a cause, it would already be considered a biomarker.
  6. Snow Leopard

    Coronavirus - worldwide spread and control

    Why are they even at the hospital getting scans if they aren't sick. There have been several "asymptomatic" cases discussed recently. The first is an individual had shortness of breath but no fever, but was considered "asymptomatic" as the doctors claimed the shortness of breath and mild cough...
  7. Snow Leopard

    Coronavirus - worldwide spread and control

    I've already addressed this nonsense about there being any significant proportion of individuals who magically have COVID without ever having any symptoms... (don't confuse reporting biases, test contamination, lack of test specificity or pre/post symptomatic cases with "asymptomatic" cases.)...
  8. Snow Leopard

    Coronavirus - worldwide spread and control

    I guess the people at the Swedish Public Health Agency are really bad at arithmetic...
  9. Snow Leopard

    Coronavirus - worldwide spread and control

    At that rate (per day), they'll achieve herd immunity in 4 years!
  10. Snow Leopard

    Coronavirus - worldwide spread and control

    At the current rate, the USA is going to overtake Sweden, Spain, Italy and France in deaths per million in a matter of 2-3 months!
  11. Snow Leopard

    The biology of coronavirus COVID-19 - including research and treatments

    https://www.nejm.org/doi/full/10.1056/NEJMoa2022483 Notable aspects: the highest dose (250 μg) caused headache in 100% of recipients, fever in over 50%, along with severe fatigue in some recipients of this dosage. One recipient in the lowest dosage (25 μg) group had a significant immunological...
  12. Snow Leopard

    The biology of coronavirus COVID-19 - including research and treatments

    It wouldn't say it is "quite common", but there are false positives, typically due to contamination. It's also possible that the first infection was SARS-2, it wasn't fully cleared and the second infection is something else.
  13. Snow Leopard

    A general thread on the PACE trial!

    It proves that no one outside of the MUS world has ever heard of the PACE trial...
  14. Snow Leopard

    Delayed Onset Muscle Soreness Is, in Fact, Neural Microdamage Rather Than Muscle Damage (2020) Sonkodi et al

    Some interesting ideas, and definitely worth studying, but I'm not convinced the issue of pain sensation is just in the muscle spindles themselves. For example, pain thresholds in muscle fascia have been shown to be increased due to DOMS, https://pubmed.ncbi.nlm.nih.gov/25519953/ Type II...
  15. Snow Leopard

    Would it be possible to train blood vessels without risking PEM?

    While cerebral vessels are structurally different (thinner walled, lack external elastic lamina and thus have a lower range of contractile diameters), they do have well developed inner elastic lamina, and it is possible to have disturbed cerebrovascular myogenic reactivity...
  16. Snow Leopard

    Performance validity test failure in clinical populations—a systematic review, 2020, Stone et al

    The alternative is to consider the "validity test" themselves may lack specificity.
  17. Snow Leopard

    Noise cancelling headphones! Oh Joy! (and other ways to block sound)

    My father has been talking about this for years (he lives in an inner-city apartment). They need to release a product already!
  18. Snow Leopard

    Australia ABC fewer flu cases due to lockdown

    The difference is probably due to travel restrictions and employers not expecting their employees to come into work when ill! ;) It remains to be seen if this proactive behaviour will remain in 2-5 years time.
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