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You mean why do they publish articles by the likes of Peter White. I think it's because they think they're giving a 'balanced' view (publishing polar opposite views) Not all the articles they publish are negative. https://www.theguardian dot com/society/chronic-fatigue-syndrome

I'm not terribly convinced about the IDO Metabolic Trap Hypothesis explaining either the epidemiology, nor the specific pattern of symptoms. I think the reasoning about genetics is a classic case of confirmation bias... The modelling is intriguing but it is fairly non-specific and could be...

It is certainly curious, the next step is to see if the results are maintained in a prospective study over time.

Beware of the sharks...

The main problem with pharmacological treatments is their efficacy was overstated. Obviously the solution is to more realistically appraise the efficacy of pharmacological treatments, not to overstate the efficacy of non-pharmacological/surgical treatments.

They are basing this on the Cochrane review - so if the review changes, then so must this commentary...

Well it has been over one month with no change...

This would be pretty obvious to users - dropouts when they check their data. I don't think these users are being misled about their heartrates, I think they're being sold ineffective junk. I find light based heart rate monitors to be unreliable and I have pale skin...

Notable for the fact that none of them are exercise physiologists. Their article makes a number of non-evidence based claims. Compliance in particular - they should note the fact that there is no data on actual compliance with the therapy, specifically actigraphy and heart rate data. Likewise...

Wow, very interesting!

They don't. https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-014-0167-5

That is not mild in any stretch of the imagination...

One problem with reducing "quality of life" or "ability to carry out day to day activities" is it doesn't take into account within-disease variation. It says nothing of the degree of variation and overlap...

Indeed. It could suggest that "moderate" and "severely" are two different diseases. Or that the results are null...

Inflammatory cytokines are not associated with (reported) fatigue in Sjögren’s syndrome either... https://link.springer.com/article/10.1007/s00296-019-04354-0 Fact is, cytokines are not a biomarker for any illness except syndromes that centre around highly elevated cytokines, such as...

The nanoneedle paper is only suggestive evidence - the samples were not blinded, we don't know what was causing the effect, the study has not been replicated. It's too little evidence to pin any hopes on at this point in time.

"on the way to feeling much better" is spin, meaning she is not yet better, but hopes to get better... :(

Well said. I too don't understand why people anyone would think the two are linked in any meaningful way.

Why then do they believe in the psychological findings that have similar flaws? Small sample sizes, weak effect sizes, poor sensitivity and specificity, (often) lack of correction for multiple outcomes and so on?

I still don't understand why people conclude that fatigue sensation is "protective"? Pain is protective. Fatigue sensation is something else. We know that fatigue sensation is associated with uncertainty about the level of motor units recruited to perform a movement at a specific force. Which is...