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  1. Arnie Pye

    Covid-19 vaccines and vaccinations

    How do people choose a vaccine to get, assuming they even have a choice? When It Comes to a Travel Restart All Vaccines Are Not Equal
  2. Arnie Pye

    The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 (...), Vinkers et al, 2021

    But they do appear to have lost their maps completely on the way to attempting evidence-based practice.
  3. Arnie Pye

    High-dose Oral Thiamine Vs Placebo for Chronic Fatigue in Patients With Quiescent Inflammatory Bowel Disease, 2021, Bager et al

    I wondered what high dose actually meant. Turns out it is between 600mg and 1800mg per day. I've come across the lower of those two doses before in other contexts, but never anything higher. I've come across thiamine being suggested as a treatment for low energy in people with hypothyroidism...
  4. Arnie Pye

    Scientists find new evidence linking essential oils to seizures

    Just for future reference for anyone reading, this is a list of essential oils from wikipedia : https://en.wikipedia.org/wiki/List_of_essential_oils When I think of essential oils I think of ones that smell nice e.g. lavender. But apparently there are quite a few that are used in cooking, and...
  5. Arnie Pye

    Symptoms of Covid-19

    I'm sure everyone has heard that Covid-19 can lead to people losing their sense of smell. Apparently one sufferer lost hers for 11 months and then regained it - and discovered that she can no longer stand the way her fiance smells. https://www.indy100.com/news/covid-aroma-fiance-b1834336
  6. Arnie Pye

    What is it like to live with medically unexplained physical symptoms? A qualitative meta-summary, 2021, Polakovská & Řiháček

    Excruciatingly painful because, being "medically unexplained", doctors refuse to prescribe pain relief that actually helps. After all, people with MUS are just drug seekers, attention-seekers, and malingerers. Aren't they? I've actually read that patients who tell doctors that paracetamol...
  7. Arnie Pye

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    @rvallee Your graphic from Eric Topol's tweet has the bottom chopped off and I think the missing info is necessary to understand what is being shown, so I've posted it again in the hope it can be seen in its entirety. But even then I'm not certain I understand what is being shown. Is column 1...
  8. Arnie Pye

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    My bold When results of blood tests are judged to be normal, I always assume this just means that the results land somewhere in the reference interval for the test. If someone has a test done with a result of X and the reference interval is B to C, then doctors declare X to be normal if it...
  9. Arnie Pye

    Functional Neurological Disorders (FNDs) in the media

    @JemPD What does "objectively well" actually mean, I wonder? I'm guessing it means that unless the problem a patient has is visible they are deemed to be well, and therefore are assumed to be malingering if they turn up at A&E. But that attitude has been standard practice for years. It...
  10. Arnie Pye

    News about Long Covid including its relationship to ME/CFS 2020 to 2021

    My bold... I've posted this before, so this isn't the first time I've made this point. It is an n=1 anecdote. This idea that "there is no identifiable organic pathology" suggests that doctors all do their utmost to look for all possibilities and find nothing. But what they really mean is...
  11. Arnie Pye

    The biology of coronavirus COVID-19 - including research and treatments

    But surely that is the ideal? Give patients drugs they can take when necessary to prevent Covid getting serious and requiring hospital/ICU stays?
  12. Arnie Pye

    Functional Neurological Disorders (FNDs) in the media

    That article is shocking in the attitude displayed by the author to patients, but sadly not remotely surprising. What does surprise me though is that apparently there is a part of the NHS I've never come across which will give people extensive investigations and long inpatient stays while the...
  13. Arnie Pye

    Editorial: Lancet Psychiatry: "Trust and transparency"

    I think that "lessons will be learned" is just a hackneyed cliché that never seems to actually change anything, whether it is in medicine, law, government or big business. As far as I am concerned, each time I hear it I know that nothing will really change to improve the situation under...
  14. Arnie Pye

    Functional Neurological Disorder in the Emergency Department, 2021, Finkelstein, Stone et al

    I've just read the following anecdote on another forum, written by a woman, naturally :
  15. Arnie Pye

    Reports from participants in GET and CBT trials

    Okay, I didn't get a full blood count either. Edit : Actually, the situation I was in was far more complicated than that sentence implies, but I don't want to go through it all on the forum.
  16. Arnie Pye

    Functional Neurological Disorder in the Emergency Department, 2021, Finkelstein, Stone et al

    What is this going to do to the death rate in women, I wonder, where death is caused by an entirely treatable condition?
  17. Arnie Pye

    Hand grip strength and fatigability: correlation with clinical parameters and diagnostic suitability in ME/CFS, 2021, Jakel,Scheibenbogen et al

    I noticed that my hand-grip strength diminished dramatically and quickly after having a hysterectomy, and I've read similar comments from other women in the same circumstances. Not only that, if I try and maintain my strongest grip (which isn't very strong at all any more) on something, e.g...
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