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  1. Mij

    Teriflunomide and EBV in a Spanish multiple sclerosis cohort: in vivo antiviral activity and clinical response, 2023, María Inmaculada Domínguez-Mozo

    I'm still convinced that if I was treated early during the viral onset that I wouldn't have developed M.E
  2. Mij

    Teriflunomide and EBV in a Spanish multiple sclerosis cohort: in vivo antiviral activity and clinical response, 2023, María Inmaculada Domínguez-Mozo

    Background: Epstein–Barr virus (EBV) and human herpesvirus 6 (HHV-6) have been associated with multiple sclerosis (MS). Teriflunomide is an oral disease-modifying therapy approved for treatment of relapsing forms of MS. In the preclinical Theiler’s murine encephalitis virus model of MS, the drug...
  3. Mij

    Neurodegeneration and its potential markers in the diagnosing of secondary progressive MS, 2023, Aleksandra Pogoda-Wesołowska et al

    A review: Approximately 70% of relapsing-remitting multiple sclerosis (RRMS) patients will develop secondary progressive multiple sclerosis (SPMS) within 10–15 years. This progression is characterized by a gradual decline in neurological functionality and increasing limitations of daily...
  4. Mij

    The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs

    The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs, 2023, Jennifer K Frediani et al Abstract Background Early in the COVID-19 pandemic, peak viral loads coincided with symptom onset. We hypothesized that in a highly...
  5. Mij

    Impaired functional sympatholysis during exercise in HFpEF: toward understanding exercise intolerance, 2023, Lisa M. Roberts et al

    I'm unable to download the PDF. https://journals.physiology.org/doi/abs/10.1152/ajpheart.00552.2023
  6. Mij

    Vaccine Effectiveness Against Long COVID in Children: A Report from the RECOVER EHR Cohort, 2023, Hanieh Razzagh et al

    Abstract Objective Vaccination reduces the risk of acute COVID-19 in children, but it is less clear whether it protects against long COVID. We estimated vaccine effectiveness (VE) against long COVID in children aged 5 to 17 years. Methods This retrospective cohort study used data from 17...
  7. Mij

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    His thread goes on and on and on . . .
  8. Mij

    Long-term Cardiovascular, Cerebrovascular, and Other Thrombotic Complications in Coronavirus Disease 2019 Survivors: A Retrospective Cohort Study

    Long-term Cardiovascular, Cerebrovascular, and Other Thrombotic Complications in Coronavirus Disease 2019 Survivors: A Retrospective Cohort Study, 2023, Jue Tao Lim et al Abstract Background Growing evidence suggests that some coronavirus disease 2019 (COVID-19) survivors experience a wide...
  9. Mij

    Covid-19 vaccination experiences

    @cfsandmore Are they also offering flu shots at the same time?
  10. Mij

    GERD, acid reflux, heartburn and hiatus hernia

    Sleeping on the left side is one of the best tips for reflux that all patients should know about.
  11. Mij

    Well-known, famous people with Covid-19 and Long Covid

    COVID-19 rampant among musicians despite “end of the pandemic” A remarkable number of musicians—from Ringo Starr to Harry Styles—have canceled concerts and other appearances in the past year due to acknowledged cases of COVID-19 or, more frequently, due to undisclosed illnesses. While...
  12. Mij

    Covid flight cancellations are back as thousands grounded after virus hits Gatwick air-traffic controllers

    Airline executives raise alarm that air traffic controller shortage will continue disruption flights for years. ”It will take five to seven years [of hiring] to break even if all goes well,” Airlines for America chief Nick Calio said at the Global Aerospace Summit held by the US Chamber of...
  13. Mij

    Covid flight cancellations are back as thousands grounded after virus hits Gatwick air-traffic controllers

    An outbreak of Covid has been blamed for the third air-traffic control slowdown at London Gatwick so far this month. Staff sickness in the control tower meant the “flow rate” of flights using the world’s busiest runway was reduced. Fifty flights to and from the Sussex airport were cancelled or...
  14. Mij

    Does ME/CFS cause permanent damage? Discussion thread

    There have also been spontaneous remissions for pw/MS, but from I've read is that it occurs in the earlier stages of relapse/onset from early intervention with disease-modifying agents. Ron Davis believes that ME/CFS can be cured because a few people who were diagnosed with ME/CFS may have had...
  15. Mij

    TMPRSS2 activation of Omicron lineage Spike glycoproteins is regulated by TMPRSS2 cleavage of ACE2, 2023, Anupriya Aggarwal et al

    Omicron has changed how the virus enters cells. Normally, the virus uses a cellular door called ACE2 and a key called TMPRSS2 to get in. Omicron has learned to pick the lock differently, using another form of ACE2 that's resistant to TMPRSS2. This allows the variant to enter cells more...
  16. Mij

    TMPRSS2 activation of Omicron lineage Spike glycoproteins is regulated by TMPRSS2 cleavage of ACE2, 2023, Anupriya Aggarwal et al

    Abstract Continued high levels spread of SARS-CoV-2 globally enabled accumulation of changes within the Spike glycoprotein, leading to resistance to neutralising antibodies and concomitant changes to entry requirements that increased viral transmission fitness. Herein, we demonstrate a...
  17. Mij

    Cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive MS, 2023, Prof Anthony Feinstein et al

    Feinstein also speaks a lot about the potential benefits of CBT and mindfulness for 'fatigue' and how clinicians can over come challenges related to access to psychotherapies so that pts can receive appropriate treatment for fatigue.
  18. Mij

    Cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive MS, 2023, Prof Anthony Feinstein et al

    Full title: Cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive MS(CogEx): a randomised blinded sham-controlled trial Summary Background Cognitive dysfunction in people with relapsing-remitting multiple sclerosis can improve with cognitive...
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