NEW & NOTEWORTHY Using novel methodology quantifying intrapulmonary shunt and alveolar dead space in COVID-19 patients up to 403 days after acute illness, 37% had increased intrapulmonary shunt and 86% had elevated alveolar dead space likely due to independent pathology. Elevated shunt was...
Abstract
Reduced exercise capacity has been suggested as a cardinal sequela of COVID-19. However, only cross-sectional approaches that either do not consider individuals with concomitant cardiorespiratory disease or account for exercise capacity before infection with severe acute respiratory...
My n=1 from taking Immunovir (Inosine Pranobex) prescribed by a virologist who saw over 200 ME pts.
Yes it was definitely a game changer for me. I went from feeling 90% improved to having a terrible relapse in 3 weeks from taking this medication that reactivated EBV and HHV6. The symptoms...
Abstract
Inosine pranobex (IP), commonly known as inosine acedoben dimepranol, isoprinosine and methisoprinol, has been proven to positively impact the host’s immune system, by enhancing T-cell lymphocyte proliferation and activity of natural killer cells, increasing levels of pro-inflammatory...
I had a neighbour who got Polio as a child, she had a relapse in her mid 40's and her legs fell out beneath her on the street. She couldn't walk. What she described was not like M.E.
Bedsores, infections and medication errors rising in Canadian hospitals amid shortage of nurses
https://www.ctvnews.ca/health/bedsores-infections-and-medication-errors-rising-in-canadian-hospitals-amid-shortage-of-nurses-1.6607334
Abstract
Introduction: Severe high-altitude illness (SHAI) and coronavirus disease 2019 (COVID-19), while differing in most aspects of pathophysiology, both involve respiratory capacity. We examined the long-term impact of COVID-19 on response to hypoxia in individuals free of symptoms but...
I experienced delayed leg muscle exhaustion one month after getting Covid after going for a walk. No fatigue, but couldn't stand for 3 weeks. Nothing I experienced resembled delayed PEM- nothing.
To add, symptoms related to autonomic dysfunction arising in para infectious or post infectious period is interesting too and still hasn't been studied very much. It is so disabling for many.
I'm more interested in the physiological processes of delayed PEM associated with M.E and other post-infectious syndromes. I hate PEM but find it fascinating.
"The University of Derby is leading the £1.2m study that involves about 100 people who have lived with the condition for more than two years".
"Patients eligible to take part in the trial will undergo a series of tests before and after they are given remdesivir, including exercise tolerability...
Abstract
Objective
There is widespread agreement about the key role of hemoglobin for oxygen transport. Both observational and interventional studies have examined the relationship between hemoglobin levels and maximal oxygen uptake () in humans. However, there exists considerable variability in...
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