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CRACKING THE CASE OF MITOCHONDRIAL REPAIR AND REPLACEMENT IN METABOLIC STRESS Salk scientists find protein FNIP1 links cellular powerhouse damage to repair during metabolic stress, with broad disease implications spanning from diabetes to cancer to neurodegeneration...

paywalled https://www.science.org/doi/10.1126/science.abj5559 Abstract Cells respond to mitochondrial poisons with rapid activation of the adenosine monophosphate–activated protein kinase (AMPK), causing acute metabolic changes through phosphorylation and prolonged adaptation of metabolism...

Also this up coming event

Congrats to Avik et al./Simmaron!! Actual good news for a change! Also nice to hear that it received excellent scores from the reviewers!

Posts moved from this thread: Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al _______________ From email: Simmaron Research Wins our 1st NIH Grant! We are proud to announce our very own Dr. Avik Roy PhD and Dr. Gunnar...

Haven’t read yet…

Further responses from RP https://forums.phoenixrising.me/threads/itaconate-shunt-now-called-infa-itaconate-shunt-part-2.89388/#post-2431109

If the Philippines offers their curriculum in English, then it is much easier for them to pass requirements in the USA, because they won’t have to pass English tests—the article implies that the UK still requires an English competency test.

I think the bigger problem is research that was never funded at the proposal stage. Ron Davis discusses this a bit in this episode of the Freakonomics podcast. https://freakonomics.com/podcast/could-long-covid-help-treat-other-chronic-illnesses/

Not sure, but I do know that on a different forum they brought up Filgotinib https://en.m.wikipedia.org/wiki/Filgotinib Some were saying that it might be helpful for very short-term use.

Merged thread They Had $350,000 and a Dream to Live Together. Could They Make It in Manhattan?, NYT Not sure where to put this—one of the people has MECFS...

Here’s the mosaic— Mosaic dysfunction of mitophagy in mitochondrial muscle disease https://www.sciencedirect.com/science/article/pii/S1550413121006367

Some very recent Robert Phair posts on PR “Chris and I recently had a great Zoom meeting with Bob Naviaux and Bhupesh Prusty and agreed on two important points: 1) our two theories are converging on the innate immune system, and 2) ME/CFS is a cell-autonomous or mosaic-dysfunctional disease...

This “university” appears to be a for-profit Christian nursing school. I think I’ve had enough for tonight.

So many typos just in the abstract. Valószínűleg az eredeti magyarban volt értelme.

13 million pounds to test metformin and alpha-lipoic acid seems excessive tbh—doesn’t really seems like a “major moment”.

https://www.nytimes.com/2023/04/04/health/alcohol-health-effects.html?unlocked_article_code=XYP_f_YN0FzRVyMpmiE8Y0JN9rGEwz5mj5P2SbeVp__hRwFmhHzxDwi6QxQl3Oyjevkn4xwD43c-SEVMe_guSkE6hMumpk6QFdTAN6vh1XBgp9rKDt4f1scFaGgR4HYgvauZeEeb5gICB7Mp8wlNqZev6xhio_AdTiqEBafJ8zoIMX8g9R6wZGh1EKk_Y2RlhC_9c7Aogv_a2...