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But on what basis is it determined that adherence is a good thing here? Other than beliefs and professional validity, i.e. it's not considered good when clients drop off therapy? Because when someone is extremely thirsty and they drink 3 glasses of water, you could say that they adhered to the...

I've seen worse, but a lot of the questions have ambiguous framing or simply rephrase other questions in a different way, and no way are those are all equal in value, so when they add up to a score, interpretation is arbitrary. I don't even understand how anyone thinks that this methodology...

So many of those numbers don't add up. And the insistence that 50% make a full recovery, which was the initial target, when there is no way to even pretend that the therapies have anything to do with any meaningful recovery. Who could have known that falsely reattributing health problems as...

Airborne and aerosol aren't jargon, FFS. This is just insulting. They lied. They kept lying. They waited until everyone moved on to admit it without consequences, knowing that plenty of people would write articles like this helping the cover up. They're still lying. So are a lot of people who...

I assume that by "psychiatric comorbidities" they mean anxiety and depression. But those aren't co-morbidities, and that almost no one seems to bother making an effort at separating the overlapping questions and the fact that most answers scoring on either dimensions will be natural consequences...

What a cheap cop out, to use the "novelty" of the virus but to use 2 years, as a point where symptoms improve in some but not all, when it's already been 4. Which of course ignores the fact that this problem has been known for decades. Medicine is really putting out a masterclass in how to...

One problem is with the highlighted portion above: well-conducted. As we have seen, there is a widespread problem in academia where "this is a great study" = "I like the conclusions" and "this is a bad study" = "I don't like the conclusions". If anything, almost all pragmatic trials are very...

Causal Inference About the Effects of Interventions From Observational Studies in Medical Journals https://jamanetwork.com/journals/jama/fullarticle/2818746 Importance Many medical journals, including JAMA, restrict the use of causal language to the reporting of randomized clinical trials...

Well it's a common word that has a more common meaning than what neurologists mean and the vast majority of MDs aren't neurologists and they will hear the common meaning of that word, they are already primed for it. As will everyone else. And of course the more problematic word is preference...

They're not playing around. This is high visibility with repetition, especially using the same imagery as from the video ad. This is smart advocacy.

Dr Unumatz agrees with this, it could be incredibly revolutional. My understanding, and I may be wrong here, is that this model is able to tell if and where a molecule will bind to a protein, one of the hardest steps in drug development. It acts as a lock and key with a humungous number of...

The reasonable response would be to acknowledge that health records are a piss-poor source of data for this purpose, invalidating the studies that relied on this method, but as is tradition, it will instead be used to argue the opposite. Echoes of "we don't like to diagnose this" behind the 90%...

17 symptoms? That's more than 5, so by the rules of the psychosomatic cinematic universe, this is clearly a case of the mass hysterias. I don't make the rules, those are the rules. It's written in plain language in all their stuff, any more than a handful of possible symptoms and that's the...

Complete waste of time and resources, yet again. But we know for a fact that the rehabilitation will be misrepresented. As will the pacing, as it's not a freaking treatment and should never be considered one. It's not possible to have lower ambition than this.

The formulaic pattern continues: take some useless treatment model, compare it to a slightly less biased approach, find that it's generally just as ineffective, but argue that both must be effective anyway, entirely out of assumptions that exercise is good for everyone. You can't get away with...

An opportunity for management of fatigue, physical condition, and quality of life through asynchronous telerehabilitation in post-acute COVID-19 patients: a randomized controlled pilot study https://www.sciencedirect.com/science/article/abs/pii/S0003999324009869 Objective To compare the...

I read many good comments about this article. It remains absurd that business and industry press tend to do better coverage of Long Covid than media with a focus on health and medicine. Doctors only seem interested when it impacts their work at their office, but for business managers, it's...

This week, DeepMind released AlphaFold v3, which has improved its accuracy in predicting protein function, but also enabled simulation of interactions between proteins and ligands (small molecules), ions (single atoms), as well as with DNA and RNA. Many (most?) drugs are ligands, so the impact...

One thing that hasn't been addressed is frankly: why? What exactly is expected that this trial will inform, when there have been hundreds such trials already? Done on a large number of variations and conditions overlapping with Long Covid, out of which exactly nothing has been learned. Because...