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I probably only understood 5 % of that. Are they saying that the root cause of PEM might be found in the brain or in the liver? Or possibly that the brain influences the liver, which in turn influences the mitochondria?

While more complex imaging protocols such as fMRI or advanced diffusion techniques may be more sensitive to subtle brain changes, in our experience their application in clinical practice remains limited. Other options, such as detailed clinical assessments and the use of validated questionnaires...

If we keep repeating it, it will become true some day…

Apparently, yes. Chronic fatigue syndrome (CFS) is a debilitating, long-term illness characterized by profound fatigue that significantly impairs daily functioning. Initially presenting as generalized weakness and lethargy, CFS may progress to a severe reduction in motivation and interest with...

Yeah, there’s an urgent need to figure out what’s wrong before we start the treatments.

Yes, I have no explanation for why it seemingly works. And the dose is really low as well, but it still lowered my standing HR by 30-40. My cardiologist speculates that my ANS (edit: autonomic nervous system) is ‘very easily influenced’ due to the relatively large response. I have no idea about...

=The Oslo Chronic Fatigue Consortium

Guess which study (9) is..

Fair question. When I stand up, and especially when I stand completely still, it feels like someone pulls a plug after a few minutes. Every ounce of energy just drains out of my body and I experience extreme weakness in my legs. I get extremely lightheaded and my vision starts to act funny...

Shared in an LC research involvement group, and asked others to share in Aus groups that they are a part of.

Me too! Your description is better.

I’m not from the US. Can someone explain what this DB is?

There’s very little information about the study, a bit concerning when it’s coming from someone that studies communication..

His source critique is on par with high schoolers - just find the sources that agree with you. I don’t understand how stuff like that gets published.

I struggle to find a single true statement in Wyller’s post. It’s like he’s living in an alternate reality.

Just a reminder that a Norwegian 13 year old boy attempted suicide after trying LP that was recommended by Wyller. This was in 2011. https://www.nrk.no/livsstil/forsokte-selvmord-etter-me-kurs-1.7891470

Answer: they did not assess the non-ME/CFS-PCS. The pre-print seemingly went beyond the evidence.

Whole blood samples from participants were allowed to clot at room temperature for at least 30 min and then centrifuged at 2000× g for 10 min at room temperature. @Jonathan Edwards could different clotting durations lead to different measurements? Room temp is also not very specific, could...

Original conclusion in abstract: New conclusion in abstract: They went from the broad ‘pathogensis of PCS’ to a more narrow ‘association with ME/CFS’. Why?