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It depends on the topic and what the protocol for that topic was. But even if it weren't in the literature search, it could be raised and discussed by any member. Also, I meant to say before, lay members are equal in every respect to professional members.

I can only speak in generalities until the minutes eventually end up in the public domain, but we certainly do consider American trials. Evidence searches typically scour all English-language publications (I think this covers translated papers too) and committee members are free to raise any...

If I have a few thousand Twitter followers, does that mean my quality of life should be really good, then? Can I get better by getting more follows? (Sorry, I couldn't resist!)

Other drugs, like amitriptyline, can have a similar effect, too: you get a nice warm glow the first couple of nights, which passes once your body seems to adjust to the tweaked neurotransmitters. My sleep and pain was the best that first night, and it's never been quite as useful ever since.

They use post-exertional 'muscle fatiguability' as a similar concept. Note that although it refers to muscles, this criterion also says that 'symptoms' worsen (it doesn't say which ones) in the following 24-48 hours. It's explicitly based on the Ramsay definition, which also refers to muscle...

Thanks. I'm following this. It's potentially useful info.

Probably physical therapist (PT) and occupational therapist (OT).

Guardian US recently had to publicly chide Guardian UK for publishing a series of transphobic articles that reiterated basically the same arguments used against gay and lesbian rights in the 1980s, and which seemed to align with recent arguments made by the American evangelical right, too. I...

I think you're right. That's where I heard it.

It could be that too. I was remembering that Cort maybe wrote something about orexin and/or leptin after eating? I can't seem to find that right now. It might none of these things, or all of these things in different people, and we might never know. But I think it's an interesting clue.

I've always wondered if the post-prandial symptoms are possibly something else, as they don't feel the same as the blood sugar dips. Maybe hormonal (to do with wakefulness, fullness, hunger, etc). You could be right about a general difficulty with metabolising carbs in some cases, though as...

I think that's probably the best way to do it. Any diet has to feel intuitive/satisfying, or you won't stick to it.

I also meant to add, I've read a few things recently that suggest that even diets of moderate-to-low carbs (say, 100-150g per day) can have a beneficial effect without going the whole hog. It might just be what we've known all along: that starchy foods are better than simple sugars at keeping...

It's interesting re-reading this thread, I think. I did keto for a good, long while, but I struggled sometimes to get the macros right (I was eating too much protein) and over-compensated by adding in too much coconut oil. As a result, I definitely gained weight towards the end when I slackened...

Thanks. I have saved this.

Could anyone summarise this? I just couldn't sit through over an hour.

This is interesting. But relatively, they should still be able so show an increase/decrease relative to averages, right? Unless the poorer signal from melanin somehow fluctuates based on other factors.

Not that I'm aware of. It was sort of glossed over.

It's in the transcript of her speech above. She sings his praises. ETA: Link here: https://www.s4me.info/threads/13-march-2019-chalder-%E2%80%98medically-unexplained-symptoms%E2%80%99-my-clinical-and-research-journey-over-30-years.5576/page-3#post-152193

It's interesting that she openly admits to working with this guy: http://gaynewsarchive.org/tag/isaac-marks/ He's notorious for his type of conversion therapy ('aversion therapy'), which involved drugs to induce nausea and causing suffering to patients.