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  1. Sean

    DecodeME - UK ME/CFS DNA study underway

    Congrats, and thanks, to all who helped bring this into existence. :thumbup:
  2. Sean

    DecodeME - UK ME/CFS DNA study underway

    https://www.theguardian.com/society/2020/jun/23/uk-to-launch-genetic-study-chronic-fatigue-syndrome-cfs "No effective treatment exists." Is The Guardian is finally getting onto the real story?
  3. Sean

    The concept of ‘illness without disease’ impedes understanding of chronic fatigue syndrome: a response to Sharpe and Greco, 2020, Lubet & Tuller

    Every cloud has a silver lining, and COVID's might be that it helps reign in the psychosomatic cult.
  4. Sean

    Comorbidities of Patients with Functional Somatic Syndromes Before, During and After First Diagnosis, 2020, Donnachie et al

    What exactly is this demonstrating? People who are sick are more likely to go to the profession supposed to deal with sick people? Diagnosis takes too long? FSS is irrelevant? But this did not trigger concerns about the FSS concept?
  5. Sean

    CBT combined with music therapy for chronic fatigue following Epstein-Barr virus infection in adolescents: a feasibility study, 2020, Wyller et al

    >that the effect can last for several years, And, of course, an "effect" is not necessarily a 'benefit'.
  6. Sean

    CBT combined with music therapy for chronic fatigue following Epstein-Barr virus infection in adolescents: a feasibility study, 2020, Wyller et al

    >At least seven randomized, controlled trials of individual CBT by ME >that the effect can last for several years, News to me.
  7. Sean

    The biology of coronavirus COVID-19 - including research and treatments

    The COVID tracing app put out by our government has been a flop. Nowhere enough people downloaded it, there was problems getting to work from the start and it still doesn't work very well, and I think only one contact has been traced by it. The government has been very quiet about it since the...
  8. Sean

    The Relationship Between Childhood Trauma and the Response to Group CBT for CFS, 2020, De Venter et al

    It may not have started out that way, but it sure has ended up becoming a deliberate cover-up exercise.
  9. Sean

    Coronavirus - worldwide spread and control

    Not normally. Though depends where you are coming from. The government is talking about fully opening the internal economy while we still have active cases, and partially reopening the borders (in a not particularly safe way). They still think they can negotiate a compromise with a virus.
  10. Sean

    Coronavirus - worldwide spread and control

    We are going to learn the hard way. Australia is about to make the same mistake. It is elimination with quarantined borders, or endless waves. There is no alternative until we have a vaccine.
  11. Sean

    Webcast: (Medically Unexplained) Physical Symptoms: A Scientist Practitioner Approach June 8 Trudie Chalder

    She did when – as one of the lead authors – she helped design the 'definitive' PACE trial. It was only after it became clear that they were not getting any positive results on any objective outcomes that they, and their like-minded colleagues, started downplaying, misrepresenting, ignoring, and...
  12. Sean

    Academic publishing: a discussion

    Wakefield, Macchiarini, PACE, and now this. There is a pattern here.
  13. Sean

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    And then some. It is astounding just how protected a species these guys are. Clearly various powers that be regard this, er, project as too important to be allowed to fail. It is anti-science.
  14. Sean

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    I want relevant subjective/self-report/QoL/PROM measures used. But only if adequately controlled by blinding or objective measures. Inadequate control, and failing to adequately account for control outcomes, is how this area of medicine got into the quagmire it is now in. Correcting that is...
  15. Sean

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    For example, when it comes to patients reporting harms. Both these examples can be measured much more objectively using a kitchen scale or an unobtrusive sleep monitor. Given they are used properly, then the bias from dodgy recall can be eliminated from the outcome (or at least reduced so far...
  16. Sean

    Webcast: (Medically Unexplained) Physical Symptoms: A Scientist Practitioner Approach June 8 Trudie Chalder

    Psycho-behavioural therapies are not objectionable, if they are appropriate, actually work, and are safe.
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