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The letter emphasises the importance of not being limited to efficacy studies. Translation: We got nothing. So we are just going to fake it.

Add in the placebo controlled Rituximab study that showed the same for placebo response in ME, and you have a powerful case for much more robust control in psycho-behavioural ME studies. The wasted money angle is potentially the most powerful we currently have to pitch to the broader non-ME...

Indeed, it becomes your 'methodology'.

Or ineffective.

Assuming the methodology was consistent for all samples (healthy v. patients), then the critical fact here is that they did find a difference. Why is another story.

Psychiatry remains primarily a means for social control, not healing the sick.

This, particularly the composition, structure, and behaviour of the amorphous component, is something I want to see investigated more thoroughly.

The beating and starving will continue until the ungrateful peasant scum submit to their superiors.

Yep. Get the bean counters onside, and we will win.

Not gonna lie. There is a bit of schadenfreude in there. But they are also potentially some of our most powerful allies.

Sorry for the individuals concerned. All the best to them. But maybe this is the the kick up the arse the UK branch of the profession needs to understand the problem and actually do something about it. One thing to be able to smear and dismiss a few patients. Quite another to do it to a huge...

I would say that was considerably more than significant. They more-or-less overturned it completely. Wessely is the one of the greatest sophists and propagandists of our age. His ability to lead an audience to a conclusion, while flattering them that they reached it independently, is...

And certainly not what the bean counters will be interested in hearing.

That is superb. Gold standard. :):):) Every person with any connection to the ME/CFS world needs to see this. Spread it far and wide, folks. Huge thanks to all who contributed. Stuff like this is what gives me hope. :thumbup: :hug: [Link to PDF containing the slides.]

It is anti-science. Not pseudo-science, not non-science. Anti-science. They are deliberately doing the opposite of robust scientific methodology. Because whenever they use robust methodology it fails to deliver any support for their pet hypothesis/model. All they are left with is sophistry and...

By solely focusing on objective outcomes and stating that subjective experiences of patients are not valid outcomes Nobody is rejecting subjective outcomes. Just unblinded subjective outcomes used on their own. That has always been the position. Stop misrepresenting it. That is not a winning...

Very interesting. :nerd::geek:

[Patho-physiological changes, for whatever reason,] in only a few cells could lead to an inflammatory response across multiple systems in the body in people with ME/CFS. As a general idea, particularly when coupled with non-linearity, this might have some value.

The vastly more methodologically robust Rituximab study completely refutes their claim. There is a sizable placebo effect in self-report for ME/CFS. Like most other conditions. Given the history of this pattern of behaviour from the psychosomatic ideologues since at least PACE (2011) it is now...

Thank you for this, Joan. :thumbup: