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No harm, the prolonged release probably won't make much difference but the dose is no big deal. AFAIK even high doses are not known to produce harmful effects, you should be able to take 50mg a day or more without doing any harm, but i wouldn't take the possibly unknown risk of doing so for no...

Not off the top of my head, years ago before my non 24 was diagnosed i was dealing with neurologists left, right and center and reading many papers on the subject but i didn't bookmark them for future reference. If you can spend some time on google scholar you may be able to find references and...

I don't know of any mechanism that can account for this, though there may be an unresearched mechanism of higher doses. But if you were given a 1mg and 5mg blinded i wonder if you would be able to tell them apart.

If your deficient in melatonin (which we might be due to Acetyl CoA reduction) then it can help, but beyond that the claims are very likely exaggerated. Also its not like most drugs/supplements, beyond 1ish mg there is no additional effect because once the receptors are saturated extra is...

This has been known for some time, in fact they seem to cause jaw fractures... i remember reading they were approved because no better option was available, not because they work great. They basically prevent bone resoption which should help because bone formation is impaired as people get older...

It regulates the body clock and has some sleep inducing properties, beyond that it won't do much else. Side effects when starting it are not uncommon and usually settle down but it does not improve the sleep quality of ME/CFS, just the two things i mentioned.

Have not read the reference or the rest of this thread but this is the quote of the day (if not month or year)! :grinning:

Fluge/Mella's pyruvate dehydrogenase paper was published less then a year ago, IMO a very important piece of the puzzle if verified Dr Davis has made some incremental steps that are not released yet, Janet talked about some of it at the other place

Is there a mechanism provided, does it activate osteocalcin?

I see. I don't know much about Ampligen so perhaps i should not comment on it, but in the end the FDA is a behemoth...

Very interesting, but if one does not do facebook are there other options?

This is very confusing to me, whats the bottom line, make donations on the 28th on facebook, get Gates match?

So they want to use Ritalin with a bunch of nutrients, try it on ME/CFS, Parkinsons and Alzheimers (casting a wide net), patent it ("KPAX002 possesses strong IP protection through 2032") then sell it. So a "drug" made with commonly available ingredients but hike the price :facepalm: Anything to...

Justifying doing harm while lying about it does not make it ok, no matter how "noble" one claims their origins to be. If one is truly that smart they should be able to see the pain they are purposely inducing instead of victim blaming then inflicting more harm while pretending they are offering...

This is a great macrocosm of the problem I disagree, the lizard one makes no sense, lizards aren't slimey enough :cautious:

I have non 24 hour circadian rhythm disorder, likely ME/CFS related and i can poke it with acetyl carnitine which increases levels of acetylcholine which is likely reduced because of lower levels of Acetyl Coenzyme A (Fluge/Mella) There is very little research on how acetylcholine affects sleep...

I hear liver contains lots of nutrients :wtf:

I've never heard of Kpax-002 till now. And i wonder why Ampligen won't do the trial the FDA wants, money, something else? And the trial that had no patients should be restarted, i bet between this and the unmentionable forum could we come up with 10 patients...

drained may not be correct, unable to utilize, but why nitpick

Atherosclerosis perhaps, but its mitigation is easy, Vitamin A, D and K2 in sufficient (but not excessive doses). If your wisdom teeth are not removed or unerupted K2 won't be tolerable to you. Stroke should also be decreased by the above vitamins Other forms of heart disease i am not too sure...