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Around the mid 1850s, Ignác Fülöp Semmelweis and Florence Nightingale led the way in advocating handwashing to prevent infections, yet it took over a century for their practices to gain widespread acceptance. Meanwhile, John Snow challenged prevailing beliefs about cholera transmission...

Trial By Error: Guardian Columnist George Monbiot Discusses His Scathing Rebuke of the Biopsychosocial Brigades–Text Version 1 Comment / By David Tuller / 23 April 2024 By David Tuller, DrPH Last week, I spoke with George Monbiot, a British investigative reporter and political activist, who...

Cluster analysis of long COVID symptoms for deciphering a syndrome and its long-term consequence Abstract The long-term symptoms of COVID-19 are the subject of public and scientific discussions. Understanding how those long COVID symptoms co-occur in clusters of syndromes may indicate the...

n=31 Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC)...

Same for me. When I finished my six one to one sessions at my local CFS clinic they wrote to my GP stating that I had "successfully completed the course" but I hadn't improved at all and they never bothered to find out if I had either then or later on. Their clinician had "successfully...

With SARS-CoV-2 being associated with a loss of sense of smell and taste could a virus cause a loss of sense of thirst? Could this be anything to do with what's being discussed in this paper? Some pwME say they have been helped with IV saline infusions though Jonathan Edwards says just drinking...

National statistics ESA: outcomes of Work Capability Assessments including mandatory reconsiderations and appeals: March 2024 Published 14 March 2024...

Not a recommendation :banghead: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex clinical condition characterized by overwhelming fatigue and associated symptoms like pain lasting greater than 6 months. ME/CFS is often initiated after an illness, exacerbated by stress...

Abstract 65 million people worldwide are estimated to suffer from long-term symptoms after their SARS-CoV-2 infection (Long COVID). However, there is still little information about the early recovery among those who initially developed Long COVID, i.e. had symptoms 4–12 weeks after infection but...

https://www.explorationpub.com/uploads/Article/A1001215/1001215.pdf Abstract Aim: It is unclear if individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with family histories of ME/CFS differ from those with ME/CFS without this family history. To explore this issue...

Yes it takes a minimum of 20 years to get justice in the UK. Hillsborough 30 years. Infected Blood transplants 30+ years. The Post Office scandal 20+ years. I'm sure there are many more.

Full title: Investigation into the restoration of TRPM3 ion channel activity in post COVID-19 condition: a potential pharmacotherapeutic target Recently, we reported that post COVID-19 condition patients also have Transient Receptor Potential Melastatin 3 (TRPM3) ion channel dysfunction, a...

Now published https://www.mdpi.com/1999-4915/16/4/572

Full title: Impaired Hand Grip Strength Correlates with Greater Disability and Symptom Severity in Post-COVID Myalgic Encephalomyelitis/Chronic Fatigue Syndrome https://www.mdpi.com/2077-0383/13/7/2153 Abstract Post-COVID syndrome (PCS) encompasses a diverse array of symptoms persisting beyond...

Science Media Centre expert reaction to study looking at long Covid subtypes and inflammatory signs in people with long Covid after Covid hospitalisation A study published in Nature Immunology looks at long Covid subtypes and inflammatory signs. Prof Eleanor Riley, Professor Emerita...

Now published https://www.nature.com/articles/s41590-024-01778-0 https://www.bbc.co.uk/news/health-68762171

Cause or Effect?

ME/CFS may be caused by an imbalance in the brain "We may have identified the physiological centre of fatigue," says the researcher behind a comprehensive study that has received a lot of attention. Vegard Bruun Bratholm Wyller is the head of research at the Department of Pediatrics at Akershus...

It would be interesting to know (but risky) if people with ME took this drug would it induce PEM without exercise.