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Documents like this really should not be behind a paywall.

One justification given by the PACE investigators, and also separately by Wessely, for the changes was that it made the results consistent with those from both the previous trials and their 'clinical experience', and that otherwise no PACE patient would be classed as improved, let alone...

Results show that those who participate in individual‐level interventions have the same levels of mental well‐being as those who do not In other words, a null result. The intervention does not work.

What were the outcome measures?

The lack of support from objective measures. No difference at 2.5 year follow up.

although it has a limited impact on fatigue and physical activity levels. No impact, according to the abstract. These findings advocate a shift in clinical practice and positioning exercise as a core component of comprehensive cancer care. Tailoring exercise regimens according to individual...

That would be the social part of psycho-social.

I first learned the term 4 years into it, and it was a real shock of recognition, light bulb turning on moment.

They are told that they are suffering from stress; that they are depressed or anxious. The implication is that their condition is psychosomatic; meaning that their emotions are manifesting as physical symptoms. This is a very invalidating experience that adds insult to injury. It is a lot worse...

This. At my worst I was never out of touch with reality, by any valid measure. It was often very difficult to process what was going on, and I made (and still make) a lot of errors in processing, but I always had my eye on the reality ball. The difference to me is that I knew full well I was...

Once upon a time neurology was absolutely sure that the reports from MS patients about monocular diplopia (double images in one eye) were impossible (inconsistent with the laws of physics, to use Stone's phrase in this paper), and indeed evidence of some form of psychopathology. Until it wasn't...

Meh. He is still clinging just as tightly onto the whole FND project. I don't see much practical distinction between incongruency and inconsistency. The comments he makes on the problems with incongruency could be applied to inconsistency too.

Once again, the only explanation that makes sense to me about findings like this is that they are downstream secondary consequences of whatever is the primary pathology. Given that ME is a specific discrete entity and underlying pathological process, then it explains why effectively all...

That is the question that needs answering.

Sadly, I have to agree with @JemPD. The risk is too high at this point. We don't have a solid evidentiary case yet about the causes and pathophysiology. The people responsible for this brutal catastrophe are still very much in power and highly influential, and have made it abundantly clear...

It would have been obvious decades ago. Even if it was a novel form of MS. Desperation, no matter how justified and compelling, is not a reason for lowering methodological quality nor undue speculation. That just plays straight into the hands of the psychosomatic club, because it legitimises...

The health care is likely to break down unless we are able to increase the level of functioning for the growing number of patients with complex, chronic illnesses. Client Satisfaction Questionnaire (CSQ-8)) (1 week), Work and Social Adjustment Scale (WSAS), Brief Illness Perception...

Sounds all too familiar.

The problem is not with EBM itself, it is with how it has been perverted.

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