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  1. Caroline Struthers

    Cochrane Survey: Provide feedback on Cochrane’s Policy on Conflicts of Interest

    This policy does nothing to address problems of the past. It continues to ignore the fact that Cochrane reviews uncritically include studies such as PACE (and also ludicruously underpowered studies that even NICE ignore) in its reviews and ignores methodological weaknesses which may or may not...
  2. Caroline Struthers

    Cochrane Survey: Provide feedback on Cochrane’s Policy on Conflicts of Interest

    Great. Another person I thought might be concerned about this bites the dust...
  3. Caroline Struthers

    Towards an institute for patient-led research - Trish Greenhalgh, BMJ blog November 12, 2019

    OK. Well I posted a comment in agreement the one that questioned whether lack of equipoise was only a problem with patients, and it didn't get through the approval stage (presumably because I mentioned PACE), so I posted another one saying I was keen to join the discussion, but having trouble...
  4. Caroline Struthers

    Towards an institute for patient-led research - Trish Greenhalgh, BMJ blog November 12, 2019

    I had to take out all mention of PACE and the Cochrane Exercise review to get my rapid response to the Risk of Bias tool paper published. 32, member: 682"]Haven't we had this problem with BMJ Blogs before...?
  5. Caroline Struthers

    Towards an institute for patient-led research - Trish Greenhalgh, BMJ blog November 12, 2019

    I will try and remember to do this, but am on leave today. Please someone else go ahead and break the news!
  6. Caroline Struthers

    Towards an institute for patient-led research - Trish Greenhalgh, BMJ blog November 12, 2019

    She's mates with Wessley. Worked together at Queen Mary?? Check this awful article out https://academic.oup.com/bmb/article/69/1/197/523356
  7. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Errr. Probably not. I think they get sent to at least the first author....
  8. Caroline Struthers

    HRA (Health Research Authority) & Bristol University's report on E. Crawley's CFS/ME Studies over registration to the Research Ethics Committee (2019)

    Do this panel of intelligent people not think that using school records to identify kids who miss a lot of school and then writing to their parents out of the blue to invite them to attend a "pilot" school clinic is something that should have ethical oversight? Where is a copy of the letters...
  9. Caroline Struthers

    Cochrane review: Homeopathy for treatment of irritable bowel syndrome, 2019, Peckham et al

    Yes. Good double blind trials of homeopathy as described above would be easy and cheap. The homeopathic medicine makers are rich and could fund these studies. Like pharma fund trials of their drugs because they have to get them licensed and so design them to favour the drug and spin the...
  10. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Finally finally after my having to remove any reference to the "P" word or the problems with the Exercise Review, and chase a couple of times, my not very rapid Rapid Response got published https://www.bmj.com/content/366/bmj.l4898/rr-3 woohoo!!!!!
  11. Caroline Struthers

    Bias due to a lack of blinding: a discussion

    The BMJ didn't publish my response even after I shortened it, so I posted it on my blog https://healthycontrolblog.wordpress.com/2019/09/30/comment-on-rob-2-a-revised-tool-for-assessing-risk-of-bias-in-randomised-trials/
  12. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Finally I submitted the rapid response to the BMJ and they didn't publish it!! I spent hours and hours honing it, and got some excellent feedback which improved it immensely, so that was a bit annoying. So I posted it on my blog...and tagged @jonathanasterne...
  13. Caroline Struthers

    RoB 2: a revised tool for assessing risk of bias in randomised trials (2019) Sterne et al.

    Thank you so much for this fantastic and clear explanation The trouble with the risk of bias tool is that the judgements are, at the end of the day, subjective (as we well know!). When these judgements are presented in individual reviews in a nice clear traffic light picture, the impression...
  14. Caroline Struthers

    Bias due to a lack of blinding: a discussion

    I am @Healthy_Control and found this excellent new thread just now without even being tagged! I have just submitted the following as a rapid response to the Risk of Bias 2 paper in the BMJ. It's amazing to see Sterne was PI on the 2012 paper... At the end of 2013 there was a debate held at...
  15. Caroline Struthers

    A Messiah in the Norwegian health system? Lightning Process and the Norwegian medical establishment - Blogpost by Nina E. Steinkopf (2019)

    Exactly right. But their reputation is as an incorruptible infallible group of independent scientists. The people with real power in the organisation are not scientists and they trust their volunteers to get it right. If the volunteer authors screw up due to incompetence or conflict of interest...
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