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  1. forestglip

    Targeted metabolomics identifies accurate CSF metabolite biomarkers [differentiating neuro-Covid from neutrotropic viral infections], 2024, Neu+

    Looks like very good separation between acute/long COVID and the other groups: Would be nice to see healthy controls included in the future.
  2. forestglip

    Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to Two Years Following COVID-19, 2023, Peluso +

    AI generated summary of Tim Henrich's talk that Amy linked to: Introduction The speaker is continuing a discussion on molecular imaging and digital spatial profiling in long COVID The talk aims to highlight the promise of immunotherapy clinical trials This presentation is part of the larger...
  3. forestglip

    Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to Two Years Following COVID-19, 2023, Peluso +

    I can't access the actual paper, but the figures are available to view in a PDF linked on the page above. Figure S4. Differences in [18F]F-AraG SUVmean uptake in certain tissues were observed when grouped by time from initial COVID-19 symptom onset to PET imaging and by Long COVID symptoms...
  4. forestglip

    Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to Two Years Following COVID-19, 2023, Peluso +

    Merged thread Now published Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection Authors (formatted by AI): Editor’s summary The term “Long Covid” covers a diverse array of symptoms that an individual might experience weeks to years after...
  5. forestglip

    How to best move the understanding of ME/CFS forward (and the forum's role in that)

    I would add the search for a viral reservoir. Labs like PolyBio have lots of ideas for studies, and more money would surely speed trials along, for example with the expensive equipment necessary for specialized scans.
  6. forestglip

    How to best move the understanding of ME/CFS forward (and the forum's role in that)

    Isn't there an issue of scientists avoiding even entering the field because of lack of research funds? Where they don't want to devote their life to something where every grant will be rejected?
  7. forestglip

    Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome, 2024, Walitt et al

    Uh oh. I've also been significantly more worried after his almost nonsensical GWI post.
  8. forestglip

    2024: Twitter campaign aimed at John Oliver and Jon Stewart

    Lots of people are commenting on the episode's Youtube and Apple Podcasts pages, asking them to also cover ME/CFS:
  9. forestglip

    Using deconditioned people as controls

    Hmm, yeah, I hadn't looked at it from the angle that many deconditioning markers might depend on normal muscle function in order to be similar across conditions (although we're not sure muscle function is even normal in ME). Another option could be people paralyzed from the neck down from spinal...
  10. forestglip

    Chris Armstrong - Melbourne ME/CFS researcher, research updates and general chat

    And please also compare to very deconditioned or other unhealthy people so we know whether or not the biomarkers are found in all deconditioned or unhealthy people. In that linked thread, we brainstormed some potential deconditioned control groups, such as bedbound hospital patients or people...
  11. forestglip

    Using deconditioned people as controls

    Merged posts And please also compare to very deconditioned or other unhealthy people so we know whether or not the biomarkers are found in all deconditioned or unhealthy people. In that linked thread, we brainstormed some potential deconditioned control groups, such as bedbound hospital patients...
  12. forestglip

    Use of EEfRT in the NIH study: Deep phenotyping of PI-ME/CFS, 2024, Walitt et al

    That's wild. It sounds like they're just saying choose whichever option returns the largest desired effect. Do they go on to explain how to decide whether or not to include single responders?
  13. forestglip

    Alzheimer’s scientists and falsified data

    Thread about another recent Alzheimer's falsified data story: Researchers plan to retract landmark Alzheimer’s paper containing doctored images
  14. forestglip

    Tool to see daily view counts on popular pages of MEpedia

    Lots of research into outbreaks over the past week. Top pages:
  15. forestglip

    Long Covid-19 and an effective lightning process intervention: A case study, 2024, Arroll et al.

    I'll paste what I previously said on the forum: I'll say that it's very hard to notice that you're doing an activity because you've already improved a small bit, and not the other way around, and I can see why someone would be absolutely sure it healed them if they stay well afterwards and...
  16. forestglip

    Dianna Cowern, Physics Girl, fundraiser 2024 and other news

    More info from the Facebook post: "Pre-recorded interviews from experts — - Linda Tannenbaum, founder and CEO of the Open Medicine Foundation. Interviewed by Derek Muller from Veritasium. - Dr. David Kaufman, an ME/CFS specialist. Interviewed by Vanessa Hill from BrainCraft. - Dr...
  17. forestglip

    Dianna Cowern, Physics Girl, fundraiser 2024 and other news

    Will be hosted by Simone Giertz and Ian Hecox (second person is half of the Smosh channel), fellow Youtubers with 2.72M and 26.7M subscribers respectively. Live stream will be on the Physics Girl Youtube channel.
  18. forestglip

    Well-known, famous people with Covid-19 and Long Covid

    The physician is Natalie Grams.
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