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  1. Hoopoe

    Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in ME/CFS - 2020 - Schreiner

    Shows how broken research is I think, but maybe I'm just underestimating the amount of work this takes. How hard is it to repeat the most important experiment in this study say 40 times or whatever passes as reasonably well powered? With the coronavirus, they can get studies done in a few weeks.
  2. Hoopoe

    Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in ME/CFS - 2020 - Schreiner

    Referring to the image above, most ME/CFS papers don't report such clear differences. That is encouraging. However it could be that the resistance to viruses is not specific to ME/CFS or indicative of viruses being the problem. It could be part of an unspecific response to illness.
  3. Hoopoe

    The iatrogenic power of labeling MUS: A critical review and meta-analysis of “diagnosis threat” in mild head injury, 2020, Niesten et al

    What about the harmful effects of people who write and believe in this stuff? How about trying to estimate how much quackery is driven by guidelines that recommend downplaying, ignoring, psychosomatizing unexplained symptoms? With patients then having no choice but to try alternative medicine.
  4. Hoopoe

    The biology of coronavirus COVID-19 - including research and treatments

    Skin manifestations suggest that https://www.the-hospitalist.org/hospitalist/article/220183/coronavirus-updates/skin-manifestations-are-emerging-coronavirus-pandemic PS: my mom also had a lot of itchy red bumps in random places on her skin in the last weeks and she thinks she's maybe had this...
  5. Hoopoe

    The biology of coronavirus COVID-19 - including research and treatments

    More hints that air pollution may be a crucial factor in lethality. https://projects.iq.harvard.edu/files/covid-pm/files/pm_and_covid_mortality.pdf
  6. Hoopoe

    Advice on mask-wearing to protect against Covid-19

    I suspect outcomes in countries with behavioural scientists or similar influencing decisions are going to be worse than those without.
  7. Hoopoe

    Covid-19 - Psychological research and treatment

    They seem to define hypochondriasis as the preoccupation to develop severe illness. That doesn't seem like a bad thing in the context of the coronavirus pandemic.
  8. Hoopoe

    Coronavirus - worldwide spread and control

    Another county that thought it was above a pandemic seems to realize it made a mistake. Sweden: 22 Scientists Say Coronavirus Strategy Has Failed As Deaths Top 1,000 https://www.forbes.com/sites/davidnikel/2020/04/14/sweden-22-scientists-say-coronavirus-strategy-has-failed-as-deaths-top-1000/
  9. Hoopoe

    Three months of bed rest induce a residual transcriptomic signature resilient to resistance exercise countermeasures, 2020, Fernandez-Gonzalo et al

    I think propensity to have PEM and sleep disruption developed together in a prodromal phase in my case, with no relationship to excessive bed rest. Only after the illness onset did I have to begin reducing my activity levels.
  10. Hoopoe

    Physical activity measures in patients with myalgic encephalomyelitis/chronic fatigue syndrome [...], 2020, Rowe et al

    On the topic of push ups and skeletal muscles. A while ago I changed my physical activity from walking to push ups and pull ups. About 15 and 5 on most days, sometimes repeated later in the day. I clearly gained muscle strength and mass but my endurance has changed very little. My feeling is...
  11. Hoopoe

    CBT combined with music therapy for chronic fatigue following Epstein-Barr virus infection in adolescents: a feasibility study, 2020, Wyller et al

    According to the CBT model, decreased physical activity would produce a worsening of CFS and PEM. That's why the aim of the therapy is ultimately to increase physical activity. What is happening here? Also note that steps per day is probably a more accurate measure of health status than...
  12. Hoopoe

    A Novel Integrative Psychotherapy for Psychogenic Nonepileptic Seizures Based on the Biopsychosocial Model, 2020, Ben-Naim et al

    The results do not support claims of effectivenes because the study is of very low quality. Curiously, most participants have "epileptic seizures" listed as comorbidity. Presumably that means the authors believe they have both organic and psychogenic seizures. Is there a simpler explanation for...
  13. Hoopoe

    A Unifying Hypothesis of the Pathophysiology of (ME/CFS): Recognitions from the finding of autoantibodies against ß2-adrenergic receptors: Wirth 2020

    I think I might be able to demonstrate with a simple test that there is a circulatory problem. If I stand on my feet and reach down to pet my cat, and then after 10 or 20 seconds bring the head back up, I feel unwell (dizzy, malaise, weak). If I repeat this posture change (giving the body some...
  14. Hoopoe

    The Arc de Siècle: functional neurological disorder during the ‘forgotten’ years of the 20th century, 2020, Stone et al

    Question: I believe in an idea that lacks credibility. How should I sell this idea to the public? Answer: Wrap it in sophisticated language to really convey how much more authoritative you are. (if there was good evidence of course you could simply present it, instead of making references to...
  15. Hoopoe

    Well-known, famous people with Covid-19 and Long Covid

    Hopefully he survives and begins to see illness and disability differently.
  16. Hoopoe

    The biology of coronavirus COVID-19 - including research and treatments

    ACE2 variants underlie interindividual variability and susceptibility to COVID-19 in Italian population https://www.medrxiv.org/content/10.1101/2020.04.03.20047977v1
  17. Hoopoe

    Coronavirus - worldwide spread and control

    Seems like the curves are flattening in multiple countries at the same time despite different starting points. Interesting. Could it have something to do with the weather?
  18. Hoopoe

    Coronavirus - worldwide spread and control

    Today the number of patients in intensive care has declined for the first time in Italy
  19. Hoopoe

    A Unifying Hypothesis of the Pathophysiology of (ME/CFS): Recognitions from the finding of autoantibodies against ß2-adrenergic receptors: Wirth 2020

    During the recent EUROMENE meeting Scheibenbogen said these antibodies belong to a group that play a role in regulating physiology. She thinks that ME/CFS is an illness where this regulatory system is not working correctly. This is how I understood what she said at least and I might be...
  20. Hoopoe

    The biology of coronavirus COVID-19 - including research and treatments

    Cats can infect each other with coronavirus, Chinese study finds https://www.theguardian.com/world/2020/apr/01/cats-can-infect-each-other-with-coronavirus-chinese-study-finds
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