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Yes, absolutely this. But, I'm not sure that this needs to be true. There could be mechanisms that stop oxygen depletion becoming so severe that tissue dies. It looks as though it is possible to have significant intestinal ischaemia for 12 hours without significant tissue damage. The pain and...

https://espen.org/documents/A174-02PaedPNGuidel_ESPGHANESPENPNGuidelines2Energy.pdf Certainly it isn't simple, but it looks as though digestion and associated processes is a significant consumption of energy. The suggestion here is that it is 10%, although it isn't clear if that is for both a...

'Intolerability of eating' as an extension of intolerance of exertion and sensory stimuli doesn't really make sense to me. I would get a pain in my gut after eating sometimes, especially in the evening. As Michelle reported, for me the pain was accompanied by a very clear need to lie down...

If people want to discuss this, we have a thread: Gastroparesis and post-prandial pain

A post on an interview with David Systrom has been moved to David Systrom, researcher, Brigham and Women's Hospital, USA

Table 2: Of the 85 students with one or more Long covid symptoms: 62% of parents agreed that the child's studying had been affected (54/85) 64% said that the child had been able to return to usual activities of daily life within a month of the illness (12/85) 14% said the the child had been...

School-based sample. It's a good idea, a prospective sample. There's just the concern that the parents of a student who drops out of school due to Long Covid may not be receiving the online communication from the school. The rate of response was pretty good. Rates of PEM weren't measured...

What it says on the tin: Prevalence and Symptom Profile of Long COVID among Schoolchildren in Vietnam, 2024, Vu et al.

:rofl: There does seem to be evidence of 'unhelpful rumination' there.

Guardian article Comments on the Guardian article are now closed, but there are 69 comments. I didn't read them all, but there are excellent comments there. Thanks to everyone who made the effort to set the record straight. Miller has been beating that particular drum for a long time. That...

I've added a tag (top left) for threads of papers with Al-Aly as an author.

Looking for Long Covid: A Clash of Definition and Study Design An article commenting on this study

We've moved posts on low blood volume to a new discussion thread on that topic: Low blood volume

That's an important reference. I meant to read it all, but have so far only got to these: These excerpts suggest that a single assessment of capacity to swallow is not sufficient when working out a suitable approach to ensuring nutrition. And, surely, sustained weight loss must be the most...

I see the benefits. Of course there are potential harms too. Social media records can easily be the subject of campaigns. For example, all the supposed testimony of recovery as a result of the Lightning Process, with testimony of harm from the therapy on social media possibly limited by...

Thanks @Sbag. Fair enough.

Low-dose naltrexone for treatment of pain in patients with fibromyalgia: a randomized, double-blind, placebo-controlled, crossover study 2024 Bested+ I think this Danish study is a high quality one. It suggests that LDN doesn't help pain, sleep, mood, function and more in people with fibromyalgia.

I like their diligent use of double blinding. In fact, I liked a lot about this study. It gives the impression of being very credible. I think the conclusion has to be that LDN is of no use for fibromyalgia - although perhaps some people will argue that the chosen standard dose doesn't work for...

That's a really interesting account. Worth clicking through to read the whole thing. I'm interested to know if others who have read the primary sources agree with it all. It notes that the name ME was applied to the initial Royal Free virus, and that the people who had ongoing symptoms were...

I assume this is Dr Strain. I know I'm commenting on incomplete information third hand, but we really need our advocates to understand that the most significant problems with the PACE trial and others like it don't include participant selection. It makes it seem that the treatments work for some...